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1. Introduction
2. Advantages of network multi-disciplinarity
3. Example to break conceptual barriers
4. Creative elements have a large dynamic centrality
5. Creative elements are central and more
6. Cellular networks
7. Definition of protein-protein interaction networks
8. Protein-protein interaction networks databases
9. Methods to identify protein-protein interactions (1)
10. Methods to identify protein-protein interactions (2)
11. Methods to identify protein-protein interactions (3)
12. Assessment of protein-protein interaction data
13. The low confidence versus low affinity problem
14. Small-worlds
15. Existence of hubs
16. Modules correspond to protein complexes
17. Lethality/Centrality
18. Date hubs and party hubs
19. Date hubs-intermodular, party hubs-intramodular
20. Rich clubs
21. Intermodular contact change affects adaptation
22. Modular overlap change affects system robustness
23. Acknowledgments

Topics Covered

• General features of networks
• Creative network nodes
• Overview of cellular networks
• Definition and databases of protein-protein interaction networks
• Main methods to identify protein interaction data and their quality
• Small worldness, hubs (date and party hubs, rich clubs) and modules of protein-protein interaction networks
• Change of modular overlaps as an efficient method of adaptation

Links

Series:

• Protein Homeostasis

Categories:

• Biochemistry
• Cell Biology
• Methods

Talk Citation

Publication History

• Published on February 2, 2012

Financial Disclosures

• Prof. Peter Csermely has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.