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- Epidemiology and Risk Factors
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41 min
1. The changing prevalence of asthma- Dr. Deborah Jarvis
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29 min
2. Recent advances in asthma genetics- Prof. Miriam Moffatt
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35 min
3. Asthma: an epidemic caused by epigenetics?- Prof. David Schwartz
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30 min
4. Role of the microbiota in asthma- Prof. B. Brett Finlay
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32 min
5. Diet and asthma- Prof. Lewis Smith
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43 min
6. Obesity and asthma- Prof. Anne Dixon
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35 min
7. Occupational asthma: management beyond the textbooks- Prof. Paul Cullinan
- Clinical Phenotypes
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42 min
8. The origins of asthma- Prof. Peter Sly
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46 min
9. Pre-school wheeze- Prof. Andrew Bush
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50 min
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24 min
11. Smoking asthmatics- Prof. Neil Thomson
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27 min
12. Aspirin exacerbated respiratory disease- Prof. Chris Corrigan
- Mechanisms of Asthma
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48 min
13. Advances in asthma: airway inflammation- Prof. William Busse
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48 min
14. The role of mast cells in asthma- Prof. Peter Bradding
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67 min
15. Dendritic cells in asthma- Prof. Bart Lambrecht
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30 min
16. The airway smooth muscle in asthma- Prof. Judith Black
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49 min
17. Role of virus infection in asthma 1- Prof. Sebastian Johnston
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27 min
18. Role of virus infection in asthma 2- Prof. Sebastian Johnston
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51 min
19. Severe asthma: characterisation, mechanisms & treatment- Prof. Fan Chung
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46 min
20. Steroid resistance in asthma: mechanisms and potential therapies- Prof. Ian Adcock
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26 min
21. Macrophage in asthma- Prof. Douglas Robinson
- Diagnosis of Asthma
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70 min
22. Physiology of asthma and involvement of small airways- Prof. Charles G. Irvin
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27 min
23. Induced sputum in asthma- Prof. Antonio Spanevello
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61 min
- Therapy and Management
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41 min
25. Pulmonary drug delivery- Prof. Anthony J. Hickey
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32 min
26. The management of chronic asthma- Prof. Mark Fitzgerald
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21 min
27. Inhaled corticosteroids and beta2-agonists- Dr. Omar S. Usmani
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20 min
28. Management of "difficult asthma"- Prof. Elisabeth Bel
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47 min
29. Management of acute exacerbations of asthma- Dr. Chris Fanta
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34 min
30. Non-pharmacological treatments for asthma- Prof. Neil Thomson
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45 min
31. Asthma: beyond the prescription- Prof. Martyn Partridge
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45 min
32. New drugs for asthma- Prof. Peter Barnes
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24 min
33. Anti-IgE therapy for asthma- Dr. Andrew Menzies-Gow
- Archived Lectures *These may not cover the latest advances in the field
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45 min
34. New drugs for asthma- Prof. Peter Barnes
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35 min
35. Asthma phenotypes in children- Prof. Andrew Bush
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40 min
36. Steroid resistance in asthma: mechanisms and potential therapies- Prof. Ian Adcock
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42 min
37. Severe asthma in children- Prof. Andrew Bush
Printable Handouts
Navigable Slide Index
- Introduction
- The need for new asthma treatments
- Poor asthma control in the real world
- Asthma deaths and therapy (UK)
- Managing mild asthma: SYGMA 1
- Managing mild asthma: SYGMA 2
- NOVEL-START study
- GINA
- Severe asthma
- Severe asthma: inflammatory phenotypes
- Unmet needs in asthma therapy
- Targeting T2 (eosinophilic) inflammation
- Interleukin-5 in asthma
- Anti-IL-5 and asthma exacerbations
- Benralizumab in severe asthma
- Interleukin-4/13 in asthma
- Dupilumab: severe asthma
- Dupilumab in asthma
- GATA-3 inhibition
- TSLP and asthma
- Anti-TSLP: severe asthma
- IL-33 and asthma
- DP2 antagonists in asthma
- Fevipiprant in severe asthma
- Targeting neutrophil inflammation
- Anti-TNF in severe asthma
- CXCR2 antagonist in severe asthma
- IL-17 expression in asthma
- Anti-IL-17R in asthma
- Macrolide in severe asthma
- New anti-inflammatory treatments
- PDE4 inhibitors
- Roflumilast in asthma
- Tiotropium in poorly controlled asthma
- Mast cell inhibitors
- Masitinib in severe asthma
- A cure for asthma?
- Conclusions: new asthma treatments
Topics Covered
- Improvements in existing therapies have been the main approach
- New classes of drug in development
- Upcoming oral and inhaled therapies that target inflammation in asthma
- Patients with severe disease
- Inflammation in severe asthma is usually corticosteroid insensitive
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Barnes, P. (2011, December 29). New drugs for asthma [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/KLFN8478.Export Citation (RIS)
Publication History
Financial Disclosures
- Peter Barnes receives research grants from AstraZeneca and Boehringer-Ingelheim and is an advisor and/or gives talks for AstraZeneca, Boehringer-Ingelheim, Covis, Novartis, Pieris and Teva.
