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Printable Handouts
Navigable Slide Index
- Introduction
- The need for new asthma treatments
- Poor asthma control
- Asthma treatment (1)
- Evolution in asthma therapy
- SMART reduces severe exacerbations
- Asthma treatment (2)
- Strategies for new asthma treatments
- Unmet needs: mild-moderate asthma
- Unmet needs: severe asthma
- New bronchodilators
- Anti-inflammatory approaches
- Prostaglandin D2 in asthma
- Targeting cytokines in asthma
- Mepolizumab in severe eosinophilic asthma
- Interleukin-13 in asthma
- IL-4/IL-13 blockade in asthma
- Anti-TNF in refractory asthma
- Anti-TNF in severe asthma
- TSLP and asthma
- Chemokine antagonists in asthma
- Dissociation of corticosteroid effects
- Dissociated corticosteroids
- New anti-inflammatory treatments
- PDE4 inhibitors
- Roflumilast in asthma
- PDE4 inhibitors: side effects
- Mast cell inhibitors
- Corticosteroid insensitivity
- Reversal of corticosteroid resistance
- Theophylline and ICS in smoking asmathics
- Macrolide in neutrophilic asthma
- A potential cure for asthma
- Conclusions: new asthma treatments
Topics Covered
- Improvements in existing therapies have been the main approach
- New classes of drug in development
- Upcoming oral and inhaled therapies that target inflammation in asthma
- Patients with severe disease
- Inflammation in severe asthma is usually corticosteroid insensitive
Links
Series:
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Therapeutic Areas:
Talk Citation
Barnes, P. (2011, December 29). New drugs for asthma [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved January 19, 2021, from https://hstalks.com/bs/2179/.Publication History
Financial Disclosures
- Prof. Peter Barnes, Speaker's Bureau: AstraZeneca, Chiesi, Boehringer-Ingelheim, Teva; Grant/Research Support (Principal Investigator): Pfizer, Takeda
New drugs for asthma
Published on December 29, 2011
41 min