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Biomedical Basics

Lipid transport

  • Created by Henry Stewart Talks
Published on May 28, 2026   5 min

A selection of talks on Cardiovascular & Metabolic

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This session centers on lipid transport, offering a structured look at the remarkable mechanisms by which lipids are transported through the body despite their water insolubility, focusing on the structure, function, and classification of lipoproteins. We will discuss the assembly, circulation, and specific roles of chylomicrons, VLDL, LDL and HDL, as well as the importance of apolipoproteins. The processes of lipid absorption, transportation via lymphatic and circulatory systems, and the metabolic pathways for both dietary and liver derived lipids will be explored. Finally, we will consider how disturbances in these pathways contribute to disease and the therapeutic approaches to lower cardiovascular risk. Lipid transport in the body is a remarkable example of molecular adaptation. Most lipids, including cholesterol and triglycerides are insoluble in water, yet the body distributes these hydrophobic molecules efficiently through the bloodstream. The principal solution is the formation of lipoproteins, particles with a lipid core surrounded by amphipathic apolipoproteins and phosphor lipids, making them soluble in plasma. This lecture will explore lipoprotein assembly, circulation, and the roles of each class. Lipoproteins are classified by density, chylomicrons, very low density, low density, and high density lipoproteins. Each has a unique lipid and protein profile reflecting distinct functions. Chylomicrons carry dietary triglycerides,

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