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- Epidemiology and Risk Factors
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41 min
1. The changing prevalence of asthma- Dr. Deborah Jarvis
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29 min
2. Recent advances in asthma genetics- Prof. Miriam Moffatt
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35 min
3. Asthma: an epidemic caused by epigenetics?- Prof. David Schwartz
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30 min
4. Role of the microbiota in asthma- Prof. B. Brett Finlay
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32 min
5. Diet and asthma- Prof. Lewis Smith
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43 min
6. Obesity and asthma- Prof. Anne Dixon
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35 min
7. Occupational asthma: management beyond the textbooks- Prof. Paul Cullinan
- Clinical Phenotypes
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42 min
8. The origins of asthma- Prof. Peter Sly
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46 min
9. Pre-school wheeze- Prof. Andrew Bush
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50 min
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24 min
11. Smoking asthmatics- Prof. Neil Thomson
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27 min
12. Aspirin exacerbated respiratory disease- Prof. Chris Corrigan
- Mechanisms of Asthma
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48 min
13. Advances in asthma: airway inflammation- Prof. William Busse
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48 min
14. The role of mast cells in asthma- Prof. Peter Bradding
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67 min
15. Dendritic cells in asthma- Prof. Bart Lambrecht
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30 min
16. The airway smooth muscle in asthma- Prof. Judith Black
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49 min
17. Role of virus infection in asthma 1- Prof. Sebastian Johnston
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27 min
18. Role of virus infection in asthma 2- Prof. Sebastian Johnston
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51 min
19. Severe asthma: characterisation, mechanisms & treatment- Prof. Fan Chung
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46 min
20. Steroid resistance in asthma: mechanisms and potential therapies- Prof. Ian Adcock
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26 min
21. Macrophage in asthma- Prof. Douglas Robinson
- Diagnosis of Asthma
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70 min
22. Physiology of asthma and involvement of small airways- Prof. Charles G. Irvin
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27 min
23. Induced sputum in asthma- Prof. Antonio Spanevello
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61 min
- Therapy and Management
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41 min
25. Pulmonary drug delivery- Prof. Anthony J. Hickey
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32 min
26. The management of chronic asthma- Prof. Mark Fitzgerald
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21 min
27. Inhaled corticosteroids and beta2-agonists- Dr. Omar S. Usmani
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20 min
28. Management of "difficult asthma"- Prof. Elisabeth Bel
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47 min
29. Management of acute exacerbations of asthma- Dr. Chris Fanta
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34 min
30. Non-pharmacological treatments for asthma- Prof. Neil Thomson
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45 min
31. Asthma: beyond the prescription- Prof. Martyn Partridge
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45 min
32. New drugs for asthma- Prof. Peter Barnes
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24 min
33. Anti-IgE therapy for asthma- Dr. Andrew Menzies-Gow
- Archived Lectures *These may not cover the latest advances in the field
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45 min
34. New drugs for asthma- Prof. Peter Barnes
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35 min
35. Asthma phenotypes in children- Prof. Andrew Bush
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40 min
36. Steroid resistance in asthma: mechanisms and potential therapies- Prof. Ian Adcock
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42 min
37. Severe asthma in children- Prof. Andrew Bush
Printable Handouts
Navigable Slide Index
- Introduction
- GINA definition of asthma
- Inflammatory subtypes in asthma
- Airway inflammation - eosinophils vs. FeNO
- FeNO levels vs. eosinophilic airway inflammation
- FeNO levels vs. neutrophilic airway inflammation
- FeNO and eosinophils
- FeNO in healthy subjects
- Factors affecting FeNO
- Factors affecting FeNO: genetic vs. environmental
- Cut-points for interpreting FeNO
- Exhaled NO and asthma diagnosis
- Exhaled NO in bronchial asthma
- FeNO in healthy/untreated asthmatic subjects
- Diagnosing asthma - conventional tests
- Diagnosing asthma: FeNO and sputum eosinophils
- Combined FeNO and spirometry
- FeNO as a diagnostic test
- Performance characteristics of FeNO
- FeNO and cough diagnosis (1)
- FeNO and cough diagnosis (2)
- FeNO in the assessment of cough
- Using sputum cell counts for asthma diagnosis
- Rat challenge - FeNO measurement
- Laboratory animal allergy (LAA)
- NO and steroid responsiveness
- FeNO measurements in anti-inflammatory therapy
- Sputum eosinophils and ICS in asthma (1)
- Sputum eosinophils and oral prednisone in COPD
- Sputum neutrophils and ICS in asthma (2)
- Hypothesis
- FEV1 change with fluticasone vs. baseline FeNO
- PC20AMP improvement with fluticasone (1)
- PC20AMP improvement with fluticasone (2)
- Predicting steroid response: EA vs. NEA
- Steroid responsiveness and non-responsiveness
- The clinical questions
- Heterogeneity of treatment response
- The PACT study
- The GOAL study
- FeNO and treatment requirements
- FeNO and steroid therapy
- Predicting relapse of asthma after ICS withdrawal
- Predicting outcome of ICS dose reduction
- FeNO as a prognostic guide
- Using FeNO to optimize steroid requirements
- Sputum cell counts and asthma management
- NO and inhaled corticosteroid (1)
- NO and inhaled corticosteroid (2)
- Cut points and their origin
- The MAP study
- The MAP study - FeNO algorithm
- The MAP study - results (1)
- The MAP study - results (2)
- FeNO measurements - using reference values
- Reference equations for FeNO
- Predicted versus absolute values (1)
- Predicted versus absolute values (2)
- High FeNO despite steroid treatment in children
- High FeNO - conclusions
- Using FeNO measurements to monitor asthma
- Exhaled NO and asthma control
- FeNO and asthma control (1)
- Using biomarkers - the timing of signal change
- Defining a 'clinically meaningful change'
- FeNO and asthma control (2)
- Predicting loss of control
- Biomarker use in complex asthma: discordance
- Dysfunctional breathing and ICS doses
- Patient K.P.
- Patient J.S.
- Applying FeNO measurements: summary (1)
- Applying FeNO measurements: summary (2)
- Conclusions
Topics Covered
- Exhaled nitric oxide (NO) in asthma
- The relationship between exhaled NO and airway inflammation
- Use of exhaled NO in diagnosis of respiratory symptoms
- Exhaled NO as a predictor of steroid responsiveness
- Strengths and weaknesses use of exhaled NO in monitoring asthma
- Guideline for the clinical application of exhaled NO
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Taylor, R. (2011, December 29). Advances in asthma: the role of exhaled nitric oxide in the assessment and management of asthma [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2025, from https://doi.org/10.69645/WRUH4110.Export Citation (RIS)
Publication History
- Published on December 29, 2011
Financial Disclosures
- Prof. Robin Taylor has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Advances in asthma: the role of exhaled nitric oxide in the assessment and management of asthma
Published on December 29, 2011
61 min
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