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Navigable Slide Index

1. Introduction
2. Population geneticists
3. Uses of population genetics
4. Mathematical models in population genetics
5. Wright-Fisher (WF) model
6. Wright-Fisher (WF) model: figure
7. Wright-Fisher (WF) model: extensions
8. Genetic drift
9. WF model: e.g. with N=6 (1)
10. WF model: e.g. with N=6 (2)
11. WF model: e.g. with N=6 (3)
12. WF model: e.g. with N=600
13. Time scaling
14. Effective population size
15. Mutation-drift balance
16. WF model with mutations
17. Allele frequency distribution over time
18. Distribution of polymorphic alleles (1)
19. Distribution of polymorphic alleles (2)
20. Population subdivision
21. Selection
22. Types of selection
23. Selection and genetic diversity
24. Tests for selection
25. Selection and human disease
26. Hardy-Weinberg Equilibrium (HWE)
27. Inbreeding
28. Coalescent theory
29. Coalescent model: Figure
30. Coalescent tree (1)
31. Coalescent tree (2)
32. The TMRCA under the coalescent
33. Coalescent tree with mutations
34. Mutations under the coalescent
35. Total branch length
36. Generalisations of the standard coalescent model
37. Further reading

Topics Covered

• Concepts in population genetics
• Wright-Fisher model
• Drift
• Effective population size
• Mutation-drift equilibrium
• Population structure
• Selection
• Hardy-Weinberg equilibrium
• Coalescent theory

Links

Series:

• Genetic Epidemiology I

Categories:

• Genetics & Epigenetics
• Methods

Talk Citation

Balding, D. and Morris, A. (2004, September 1). Introduction to population genetics 1: single locus [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 21, 2024, from https://doi.org/10.69645/YZSY3886.
Export Citation (RIS)

Publication History

• Published on September 1, 2004
• Archived on February 25, 2021

Financial Disclosures

• Prof. David Balding has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
• Dr. Andrew Morris has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.