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1. Introduction
2. Outline
3. Why treat epilepsy?
4. The risk of seizure recurrence
5. Who may not need AEDs
6. Response to first ever AED
7. Which AED is best?
8. Considerations in the choice of AED
9. Mechanism of AEDs action and clinical efficacy
10. Three generations of AEDs (1)
11. Major first generation AEDs
12. Three generations of AEDs (2)
13. Major second generation AEDs
14. Three generations of AEDs (3)
15. Third generation AEDs (1)
16. Third generation AEDs (2)
17. Which AED is used for focal seizures?
18. Which AED is used for generalized seizures?
19. Starting dose, titration and drug interaction
20. Limited effectiveness of dose increase
21. Which dose is optimal?
22. Adverse events of AEDs
23. AED associated disease
24. Pharmacological treatment in special populations
25. Effect of AEDs on other drugs
26. Metabolic consequences: enzyme-inducing AEDs
27. ILAE definition of drug resistant epilepsy
28. Drug resistant epilepsy
29. No. of prior life time AEDs and drug response
30. Why combine AEDs?
31. Placebo-corrected efficacy of AEDs
32. Add on or substitution?
33. Depression and suicidality
34. Natural history of treated epilepsy
35. AEDs for the elderly
36. Stopping AEDs (1)
37. Stopping AEDs (2)
38. Visions for the future
39. Summary

Topics Covered

• Current drug treatment of epilepsy
• Four major questions
• How and when to start AEDs?
• Which AED?
• How to optimize the benefit/risk balance of pharmacological treatment for your patient?
• How and when to stop AEDs?
• What are the unmet need of current treatment and what to do about it?

Links

Series:

• Epilepsy and Seizures

Categories:

• Clinical Practice
• Neuroscience
• Pharmaceutical Sciences

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on May 3, 2011

Financial Disclosures

• Prof. Dieter Schmidt has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.