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1. Introduction
2. Social perception
3. The social brain
4. Regional brain localization of social perception
5. Autism spectrum disorder
6. Eye contact deficit in autism
7. Outline
8. Recognition of biological motion
9. Biological vs. non-biological motion
10. The biological motion area
11. The motion processing area
12. Additional functions of the posterior STS
13. The congruent vs. incongruent paradigm
14. Hemodynamic response in the right vs. left pSTS
15. Right posterior STS region
16. Is the pSTS involved in understanding emotions?
17. Congruent vs. incongruent study (1)
18. Congruent vs. incongruent study (2)
19. Connecting eye-gaze with mental state
20. Is pSTS dysfunction involved in autism
21. The interpretation for intentions method
22. A failure of interpretation for intentions in autism
23. Incongruent-congruent delay vs. ADI-R impairment
24. Congruent vs. incongruent study (3)
25. Replication of finding in typical participants
26. Congruent-incongruent % BOLD signal change
27. Is genetic polymorphism involved in heterogeneity?
28. Serotonin transporter genes and autism
29. Encouraging autistic people to inspect the eyes
30. Hypoactivation of the Fusiform Gyrus (FFG)
31. Looking at faces in autism and the FFG
32. Experimentally modifying visual scanpaths
33. Eye movement manipulation
34. Free viewing conditions
35. Visual scanpath modification effects in FFG
36. Insights from the developing social brain
37. Behavioral training for fMRI (1)
38. Behavioral training for fMRI (2)
39. STS response to biological motion in autism
40. Biological vs. non-biological motion (3)
41. No STS distinction of biological motion in autism
42. Normal STS response to general motion in autism
43. Emotion regulation in children with autism
44. Emotional go/no go task
45. Wall of fame
46. Emotion regulation task-scheme
47. Children comments
48. Emotion regulation task-results
49. Acknowledgments (1)
50. Acknowledgments (2)

Topics Covered

• The social brain
• Regional localization of areas involved in social perception
• What brain mechanisms support recognition of biological motion?
• Posterior STS region
• Does the posterior STS exhibit differences in activity that depend on the previous emotional context related to understanding other's preferences?
• Eye-gaze processing deficits in autism
• Can we normalize FFG activity in participants with autism by experimentally modifying visual scanpaths?
• Insights from the developing social brain
• Behavioral training for fMRI
• Does the STS respond selectively to biological motion in children with autism?
• The development of brain mechanisms for emotion regulation in children with and without autism

Links

Series:

• Autism and Autism Spectrum Disorders

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Pelphrey, K. (2010, September 14). Neural signatures of atypical social brain development in autism [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/GEHW1938.
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Publication History

• Published on September 14, 2010

Financial Disclosures

• Dr. Kevin Pelphrey has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.