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Printable Handouts
Navigable Slide Index
- Introduction
- Alzheimer disease pathology
- Tau-containing tangles and related lesions
- Aberrant splicing of tau gene can cause tauopathy
- Pathogenic mechanisms in tauopathy
- Targets for drug development in the tauopathies
- Reduction of tau by immunotherapy
- Phospho-tau as a target
- GSK3 inhibition via lithium
- Tau-microtubule interaction as a target
- Degradation of abnormal tau as a target
- Disaggregation of tau as a target
- Enhanced neuroprotection as a target
- Summary
Topics Covered
- Tauopathies
- Alzheimer's Disease and frontal temporal lobe dementia
- Pathogenic mechanisms
- Therapeutic approaches for the tauopathies
Links
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Therapeutic Areas:
Talk Citation
Duff, K. (2010, August 26). Pathogenic mechanisms and therapeutic approaches for the tauopathies [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/CVYV4161.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Karen Duff has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Pathogenic mechanisms and therapeutic approaches for the tauopathies
Published on August 26, 2010
19 min