Biomedical Basics

Second messengers: cAMP, IP3, calcium

  • Created by Henry Stewart Talks
Published on January 28, 2026   4 min

A selection of talks on Cardiovascular & Metabolic

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This presentation will examine second messengers with a focus on the essential roles of three major second messengers, Camp IP three and calcium ions in cellular signaling. We will examine how each messenger is generated in response to external signals, activates specific intracellular pathways, and orchestrates diverse cellular processes. By discussing their interactions and regulatory mechanisms, we will highlight the complexity and importance of second messenger systems in cell function and disease. Today, we'll explore the vital roles of three second messengers, cyclic AMP E camp in oscitl one, four, five trisphosphate, IP three, and calcium ions in cellular signaling. Second messengers relay signals from cell surface receptors to internal targets, amplifying and integrating information to drive proper cellular responses. By focusing on CAP, IP three, and calcium, we see how external cues are swiftly converted into specific intracellular actions through coordinated signal transduction pathways. Let's first consider CAMP, the classic second messenger discovered by Earl Sutherland. Camp production begins when a signal like adrenaline binds to a G protein coupled receptor on the membrane, activating a G protein that stimulates a dnelial cyclase to convert ATP into cAMP. Camp activates protein kinase A, which phosphorylates proteins, promoting glycogen breakdown, and inhibiting synthesis. Camp's signal is amplified dramatically,

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Second messengers: cAMP, IP3, calcium

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