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About Biomedical Basics
Biomedical Basics are AI-generated explanations prepared with access to the complete collection, human-reviewed prior to publication. Short and simple, covering biomedical and life sciences fundamentals.
Topics Covered
- DNA double helix structure
- Nucleotide composition and base pairing
- DNA replication mechanisms
- Gene expression processes
- DNA packaging and chromatin regulation
Talk Citation
(2026, January 28). DNA structure and function [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved February 9, 2026, from https://doi.org/10.69645/LNDX2838.Export Citation (RIS)
Publication History
- Published on January 28, 2026
Financial Disclosures
A selection of talks on Genetics & Epigenetics
Transcript
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0:00
The topic of DNA structure and
function will be explored,
including its double
helix arrangement,
nucleotide composition,
and base pairing rules essential
for genetic stability.
We will discuss the mechanisms
of DNA replication,
emphasizing enzyme
involvement and
fidelity in genetic inheritance.
The process of gene expression,
transcription and translation
will also be explained,
highlighting how
genetic information
is converted into proteins.
Finally, we will explore
how DNA is packaged in
eukaryotic cells and how
this packaging regulates
gene accessibility
and expression.
Deoxyribonucleic acid or DNA is
the molecule that stores
genetic information
for all living organisms,
mainly found in the nuclei
of eukaryotic cells.
DNA consists of
extremely long molecules
that if stretched,
would span nearly 2 meters
in a single human cell.
It's double helic structure,
proposed by Watson
and Crick in 1953,
with Rosalind Franklin's
key X ray work,
features two
intertwined strands,
sugar phosphate backbones
and paired nucleotide bases,
ensuring stable, accessible
genetic information.
DNA is made of repeating
subunits called nucleotides,
each containing a
deoxyabos sugar,
a phosphate group, and one of
four nitrogenous bases adenine,
thymine, cytosine, or guanine.
The double helix allows for
complementary base pairing,
adenine pairs with thymine
and guanine with cytosine.
This base pairing, described by
Chargaff's rules is vital for