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1. Introduction
2. What is biophotonics?
3. Why use biophotonics?
4. Need for biophotonics in medicine
5. Photomedicine in cancer
6. In vivo optical imaging in cancer
7. Research in nano-biophotonics
8. Endoscopic optical biopsy
9. Hypericin - a novel photosensitizer
10. Real-time fluorescence diagnostic system (1)
11. Real-time fluorescence diagnostic system (2)
12. Macrosocopic fluorescence imaging with hypericin
13. White light and fluorescence of oral lesions
14. Image analysis algorithm
15. Diagnostic accuracy of cancer detection
16. Macroscopic fluorescence analysis
17. Microscopic fluorescence analysis
18. Fluorescence cytology images in hypericin ex-vivo
19. Ex-vivo optical methods
20. Endoscopic autofluorescence imaging
21. Optimal excitation/emission wavelengths
22. Autofluorescence lifetime studies
23. Towards a 3D fluorescence diagnostic system
24. Laser confocal endomicroscope
25. The novel rigid confocal endomicroscope system
26. In-vivo cellular confocal endomicroscopy
27. Extension to a 3D system
28. Ex-vivo imaging of the mouse tongue
29. Clinical laser confocal endomicroscope
30. Optical coherence tomography (OCT)
31. OCT vs. confocal imaging
32. OCT images of the eye
33. Optical coherence tomography in NCC
34. OCT image of subcutaneous tumour
35. Oncological applications in OCT
36. OCT-MEMS scanning mirror technology
37. Patented MEMS probe technology
38. Nano-oncology
39. Nano conjugated biomarkers to image cancer cells
40. Metallic nanostructures as contrast agents
41. Gold nanoshells in cancer imaging and therapy
42. Gold nanoshell and nanorod antennas
43. Combine structural and molecular imaging
44. Bioconjugated gold nanoshells as contrast agents
45. Raman spectroscopy
46. Surface enhanced Raman spectroscopy (SERS)
47. Intensity comparison of Au NP and QD705
48. Applications of SERS
49. SERS tags for cellular targeting and quantification
50. In vivo cancer targeting using SERS
51. A fiber optic probe with SERS-nanoparticle
52. SERS microfluidic method for ex-vivo bio-sensing
53. SERS bio-sensing
54. Acknowledgements

Topics Covered

• What is biophotonics?
• The need for biophotonics in medicine
• Photomedicine in cancer
• In vivo optical imaging in cancer detection
• Endoscopic optical biopsy
• Real-time clinical fluorescence diagnostic system
• Image analysis algorithm
• Diagnostic accuracy of bladder and oral cancer detection using fluorescence
• Macroscopic fluorescence analysis in the oral cavity and cervix
• Ex-vivo optical methods
• Autofluorescence lifetime studies
• Towards a 3D fluorescence in vivo cellular diagnostic system
• Optical coherence tomography (OCT)
• OCT vs. confocal imaging
• Nano-oncology
• Nano-based imaging
• Nano-drug delivery systems

Links

Series:

• Medical Imaging

Categories:

• Cancer
• Clinical Practice
• Methods

Therapeutic Areas:

• Oncology

Talk Citation

Publication History

• Published on September 29, 2010

Financial Disclosures

• Prof. Malini Olivo has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.