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Printable Handouts
Navigable Slide Index
- Introduction
- We have many ancestors
- Patterns in our DNA
- From the pattern to the process
- Morphological differences
- Each group harbours extensive diversity
- Analyses of morphological traits
- The problem with morphological traits
- Estimating variances from sequence comparisons
- Variation within and between populations
- Independent studies yield vey similar results
- What does this mean in practice?
- Mind the numbers
- Clustering genotypes or haplotypes
- Structures inferred from SNPs, haplotypes, CNV
- The problem with genetic traits
- Continent specific alleles
- The association of alleles in long haplotypes
- Genetic diversity outside Africa
- How is the human population structured?
- Models of human evolution
- A model of isolation by distance
- Evidence for dispersal from Africa
- Genetic diversity reflects patterns of migration
- Human evolution and variation (1)
- Human evolution and variation (2)
- Human evolution and variation (3)
- Linguistic and genetic differences are correlated
- Serial coalescent simulation and ABC
- Reconstructing the maternal genealogy (1)
- Reconstructing the maternal genealogy (2)
- An example
- Mutation
- First DNA sequence of a Neandertal
- Neandertals not modern Europeans' ancestors (1)
- Neandertals not modern Europeans' ancestors (2)
- Why is the human population structured this way?
- Summary
- References: patterns
- References: processes
Topics Covered
- Human population structure
- Racial catalogs based on morphology
- Genetic variation within and between populations
- Genetic clustering of human populations
- Isolation by distance
- A recent demographic expansion from Africa
- Testing evolutionary hypotheses by coalescent simulation
- Ancient DNA
Talk Citation
Barbujani, G. (2009, December 28). Inference on human history through DNA [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/NWLP5823.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Guido Barbujani has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.