• Basic Concepts
• 19 min
  1. Molecular structure of the human genome

  • Prof. Jonathan Wolfe
• 31 min
  2. Introduction to mutation and disease

  • Prof. Jonathan Wolfe
• 26 min
  3. Introduction to genetic diseases

  • Prof. Jonathan Wolfe
• 26 min
  4. Historical introduction to human diversity I

  • Prof. Dallas Swallow
• 28 min
  5. Historical introduction to human diversity II

  • Prof. Dallas Swallow
• 23 min
  6. Introduction to cytogenetics 1

  • Dr. Sioban SenGupta
• 15 min
  7. Introduction to cytogenetics 2

  • Dr. Sioban SenGupta
• 16 min
  8. Introduction to cytogenetics 3

  • Dr. Sioban SenGupta
• 42 min
  9. The Y-chromosome

  • Prof. Mark Jobling
• 42 min
  10. Mitochondrial DNA, molecular genetics and human mitochondrial diseases

  • Prof. Immo Scheffler
• 66 min
  11. Mechanisms of DNA repair by recombination

  • Prof. James Haber
• 26 min
  12. Techniques utilized in molecular genetics

  • Dr. Cecil Lewis
• 36 min
  13. Genome mapping

  • Dr. Simon Gregory
• 35 min
  14. Copy number variation

  • Dr. Ömer Gökçümen
• Genetics and Disease
• 45 min
  15. Genetic association studies

  • Prof. David Balding
• 42 min
  16. Quantitative genetics and multifactorial inheritance

  • Dr. Lara Bauman
• Human Evolutionary Genetics
• 34 min
  17. Population genetics

  • Dr. Murray P. Cox
• 59 min
  18. Inference on human history through DNA

  • Prof. Guido Barbujani
• 37 min
  19. Human adaptation

  • Prof. Rasmus Nielsen
• Specialized Topics
• 44 min
  20. Accessing and using ENCODE data

  • Prof. Peggy Farnham
• 44 min
  21. Pharmacogenetics

  • Prof. Ann Daly
• 33 min
  22. Genetics in forensics

  • Dr. Angel Carracedo
• 29 min
  23. The development and evolution of human gene therapy

  • Prof. Theodore Friedmann
• 33 min
  24. Next generation sequencing technologies

  • Dr. Krishna Veeramah

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Meiosis
3. Genetic diversity
4. Meiosis I, prophase I
5. Meiosis I, metaphase I - telophase I
6. Meiosis II
7. Synapsis
8. Crossing over/recombination (1)
9. Crossing over/recombination (2)
10. Chiasmata
11. Sex chromosomes
12. Cell cycle checkpoints
13. Meiosis check points
14. Aneuploidy causes
15. Non-disjunction during meiosis
16. Distribution of non-disjunction
17. Parental origin of aneuploidy
18. Gametogenesis
19. Gametogenesis in males
20. Female human embryo - stages in gonad
21. Oogenesis
22. Gametogenesis in females
23. Differences in gametogenesis
24. Aneuploidy
25. Maternal age specific estimates of trisomy
26. Production line hypothesis (PLH)
27. Depleted oocyte hypothesis (DOH)
28. Down syndrome type
29. Chromosome abnormalities in humans
30. Chromosome abnormalities in miscarriages
31. Chromosome abnormalities in newborns
32. Chromosome abnormalities

Topics Covered

• Genetic diversity
• Meiosis I
• Meiosis II
• Synapsis
• Recombination
• Chiasmata
• Sex chromosomes
• Cell cycle checkpoints
• Meiosis check points
• Causes of aneuploidy
• Non-disjunction during meiosis
• Disruption of non-disjunction
• Parental origin of aneuploidy
• Gametogenesis
• Oogenesis
• Impact of maternal age
• Production line hypothesis
• Depleted oocyte hypothesis
• Down syndrome
• Chromosome abnormalities in humans, miscarriages and newborns

Links

Series:

• Introduction to Human Genetics

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on January 6, 2010

Financial Disclosures

• Dr. Sioban SenGupta has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.