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1. Introduction
2. The genus Haemophilus
3. Bacillus influenzae or Pfeiffer's bacillus
4. Haemophilus is not the cause of influenza
5. Haemophilus influenzae serotypes
6. H. influenzae serotype b (Hib) diseases
7. Virulence determinants of Hib
8. Immunization strategies for Hib
9. Invasive Hib disease in the United States
10. Hib disease - the global burden
11. Hib vaccine programs
12. Other H. influenzae serotypes
13. Hamilton O. Smith, Nobel Laureate
14. H. influenzae, strain Rd
15. Nontypeable H. influenzae (NTHi)
16. Otitis media
17. NTHi strain 86-028NP and strain Rd
18. Putative virulence determinants of NTHi
19. Basic structure of the H. influenzae LOS
20. LOS oligosaccharide structures
21. Sialic acids and virulence
22. Phosphorylcholine
23. Phosphorylcholine and virulence
24. Phase variable gene expression
25. Simple sequence repeats
26. Iron utilization systems
27. Resistance to effectors of innate immunity
28. Expression modulation of innate immunity effectors
29. Adhesins in NTHi 86-028NP
30. Expression of Tfp by 86-028NP
31. Type IV pili and biofilms (1)
32. Type IV pili and biofilms (2)
33. Other Haemophilus species
34. Haemophilus ducreyi
35. Haemophilus ducreyi infection
36. Experimental human infection with H. ducreyi
37. Histopathology of pustules
38. Putative virulence determinants of H. ducreyi
39. Summary

Topics Covered

• Hemophilus influenzae
• Virulence determinants
• Immunization strategies
• Hib
• Other serotypes
• Basic structure of the H. influenzae LOS
• Sialic acids and virulence
• Phosphorylcholine (PCho) and virulence
• Phase variable genes
• Iron utilization systems
• Resistance to effectors of innate immunity
• Adhesins
• Other Haemophilus species associated with human health and disease
• Haemophilus ducreyi

Links

Series:

• Molecular Basis of Bacterial Infection

Categories:

• Clinical Practice
• Microbiology

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Publication History

• Published on November 3, 2009

Financial Disclosures

• Prof. Robert Munson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.