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Printable Handouts
Navigable Slide Index
- Introduction
- Infectious diseases
- Bacterial diseases
- Steps to an infection
- Bacterial pathogenesis
- Introduction to toxins
- Exotoxin
- Endotoxins
- Mechanisms of adherence
- Electron microscope image of pili
- BFP and adhesion
- Type III secretion systems
- Pathogenic E.Coli - O157
- Type III secretion in E. Coli O157 (1)
- Type III secretion in E. Coli O157 (2)
- Translocon and effector proteins
- Model of EPEC pedestal formation
- Cytoskeletal proteins recruited to the pedestal
- E. coli - induced cytoskeletal rearrangements
- TIR delivery to host cell via type III system
- Life inside a host cell - intracellular pathogens
- Intracellular survival strategies
- Salmonella enterica
- Salmonella - an intracellular pathogen
- Salmonella typhimurium
- Salmonella's two type III secretion systems
- Salmonella invasion (1)
- Salmonella invasion (2)
- SCV trafficking in epithelial cells
- Intracellular Salmonella
- Salmonella evade host defenses
- Intracellular Listeria monocytogenes
- Listeria intracellular movement
- Regulation of virulence factors
- Avoiding innate defenses
- Avoiding acquired immunity
- Anti-phagocytosis
- Yersinia inhibition of phagocytosis
- Role of the microbiota
- Microbiota disturbed in Citrobacter infection
- Antibiotics
- Antibiotic mechanisms
- Superbugs
- Vaccines
- Top four bioterrorist diseases
- Conclusions
Topics Covered
- Overview of bacterial diseases and virulence factors
- Toxins
- Adherence mechanisms
- Type III secretion systems
- Intracellular survival mechanisms
- Avoiding the immune system
- Impact of microbiota
- Antibiotics
- Vaccines -Bioterrorism
Links
Series:
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Talk Citation
Finlay, B.B. (2009, October 29). The molecular basis of bacterial pathogenicity: an overview [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved June 10, 2023, from https://hstalks.com/bs/1462/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. B. Brett Finlay has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.