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Navigable Slide Index

1. Introduction
2. Infectious diseases
3. Bacterial diseases
4. Steps to an infection
5. Bacterial pathogenesis
6. Introduction to toxins
7. Exotoxin
8. Endotoxins
9. Mechanisms of adherence
10. Electron microscope image of pili
11. BFP and adhesion
12. Type III secretion systems
13. Pathogenic E.Coli - O157
14. Type III secretion in E. Coli O157 (1)
15. Type III secretion in E. Coli O157 (2)
16. Translocon and effector proteins
17. Model of EPEC pedestal formation
18. Cytoskeletal proteins recruited to the pedestal
19. E. coli - induced cytoskeletal rearrangements
20. TIR delivery to host cell via type III system
21. Life inside a host cell - intracellular pathogens
22. Intracellular survival strategies
23. Salmonella enterica
24. Salmonella - an intracellular pathogen
25. Salmonella typhimurium
26. Salmonella's two type III secretion systems
27. Salmonella invasion (1)
28. Salmonella invasion (2)
29. SCV trafficking in epithelial cells
30. Intracellular Salmonella
31. Salmonella evade host defenses
32. Intracellular Listeria monocytogenes
33. Listeria intracellular movement
34. Regulation of virulence factors
35. Avoiding innate defenses
36. Avoiding acquired immunity
37. Anti-phagocytosis
38. Yersinia inhibition of phagocytosis
39. Role of the microbiota
40. Microbiota disturbed in Citrobacter infection
41. Antibiotics
42. Antibiotic mechanisms
43. Superbugs
44. Vaccines
45. Top four bioterrorist diseases
46. Conclusions

Topics Covered

• Overview of bacterial diseases and virulence factors
• Toxins
• Adherence mechanisms
• Type III secretion systems
• Intracellular survival mechanisms
• Avoiding the immune system
• Impact of microbiota
• Antibiotics
• Vaccines -Bioterrorism

Links

Series:

• Molecular Basis of Bacterial Infection

Categories:

• Cell Biology
• Microbiology

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Finlay, B.B. (2009, October 29). The molecular basis of bacterial pathogenicity: an overview [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved June 10, 2023, from https://hstalks.com/bs/1462/.
Export Citation (RIS)

Publication History

• Published on October 29, 2009

Financial Disclosures

• Prof. B. Brett Finlay has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.