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Biomedical Basics

DNA Mutations

  • Created by Henry Stewart Talks
Published on December 31, 2025   4 min

A selection of talks on Genetics & Epigenetics

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This overview addresses mutations with particular emphasis on the definition and significance of mutations as changes in DNA that can profoundly affect organisms. We'll discuss different types of mutations, including point mutations, insertions, and deletions, and how these alter genetic information and protein function, sometimes leading to disease. The sources of mutations, whether spontaneous or triggered by environmental factors, will be explored along with their roles in heredity, genetic disorders, and evolution. Finally, we'll highlight how understanding mutations deepens our knowledge of health, disease, and medical advances. A mutation is any permanent alteration in a cell's DNA sequence. DNA codes for proteins are essential to an organism's function and development. So even small changes can have profound effects. Mutations are a natural part of life, arising from internal cellular processes or environmental factors like radiation, chemicals, or viruses. Mutations also drive evolution and genetic diversity. Let's take a closer look at DNA mutations. Mutations can change DNA sequences in several ways. Point mutations involve a single base pair change, like a single-letter typo in a text. Insertions add base pairs while deletions remove them. Insertions and deletions can be disruptive if they shift the genetic reading frame, possibly producing a different or non-functional protein. The consequences depend on where the mutation

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