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Biomedical Basics

CRISPR-Cas9 and gene editing

  • Created by Henry Stewart Talks
Published on November 30, 2025   4 min

A selection of talks on Infectious Diseases

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The following session will cover CRISPR-Cas9 and Gene Editing Basics within the context of this subject, focusing on the basics of CRISPR-Cas9, its origins as a bacterial defense system, and how it enables precise gene editing. We will discuss the molecular mechanism by which CRISPR-Cas9 targets and alters DNA, as well as its wide-ranging applications in research, medicine, and agriculture. The presentation will address the key risks, ethical concerns, and societal debates surrounding this technology. Finally, we will explore future advancements and the importance of balancing innovation with responsibility in genome engineering.. To begin, CRISPR-Cas-nine is a powerful gene-editing tool. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, a natural defense system in bacteria. It acts as adaptive immunity, enabling bacteria to store viral DNA snippets in their genome to recognize and combat repeat invaders. The Cas-nine enzyme functions as molecular scissors for gene editing. Together, CRISPR and Cas-nine allow scientists to target DNA sequences with unprecedented precision, greatly accelerating genetic research. The true power of CRISPR-Cas-nine lies in its ability to target specific DNA sequences within the genome. Guided by a designed RNA molecule, the Cas-nine enzyme is directed to the desired DNA site, where it creates a double-stranded break. The cell detects this break and tries to repair it.

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