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0:00
Hello. My name is Eric Jauniaux.
I'm a professor at
the Elizabeth Garrett
Anderson Institute for
Women's Health at
University College London.
I have the great
honor and pleasure
to present to you a
new lecture called
Congenital Anomalies
of Placentation.
This is my second lecture
for the Henry Stewart.
The first one was on
normal placentation.
0:24
In the first part,
I will talk about the most
important of these anomalies,
which is placenta previa,
and then in the second part,
we'll have a look at new
complications of placentation,
and then, we'll have a look at
the anomalies of
the umbilical cord.
Overall, these congenital
anomalies of placentation
affect about 1-2%
of pregnancies.
They're influenced by
the mode of conception.
They're much higher in in vitro
fertilization conceptions,
and they are associated with
a high perinatal
mortality and morbidity.
It's absolutely important
that they're being
diagnosed before delivery,
because the mortality,
of course, increases if they
are only found at delivery.
1:06
The main anomalies of
placentation are placenta previa,
placenta accreta spectrum,
and the anomalies of the
umbilical cord insertion.
1:16
Let's start with
placenta previa.
1:20
What is the definition
and prevalence?
It is the development
of the placenta
in the lower uterine segment,
so the lower part of the uterus,
and it has a reported
prevalence of about
1 in 50 to 1 in 500 pregnancies
in the second half of pregnancy.
It depends obviously on
the gestational age,
as the interaction between
the placenta and the uterus
anatomically will change
as pregnancy advances,
and the use of an ultrasound
protocol, a standardized one,
and risk factor in
the population.
