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1. Introduction
2. Long-standing questions about race
3. Fundamentals of DNA and the genome
4. Human genome sequence
5. DNA sequence variation (12,987 base pairs)
6. Essential features of human genomic diversity
7. Nucleotide diversity within and between continents
8. Expected human nucleotide diversity
9. Nucleotide diversity suggests a small population
10. Venn diagram of nucleotide diversity
11. Pattern of variation in other DNA data sets
12. STR data set
13. Populations included (STR analysis)
14. Relationships among human populations (1)
15. Major long-range human migrations
16. Do race concepts fit the pattern of variation?
17. Definitions of race
18. Race concepts and actual pattern of diversity
19. Relationships among human populations (2)
20. Can genetic markers identify populations?
21. Allocation of individuals to genetic clusters
22. Inferring population membership from DNA markers
23. Principal pathway of ethanol metabolism
24. Allele frequencies at the ALDH2 locus
25. Information content for genetic markers (1)
26. Information content for genetic markers (2)
27. Predictive value of "genetic ancestry"
28. Diabetes risk in Indians with European ancestry (1)
29. Diabetes risk in Indians with European ancestry (2)
30. Conclusions

Topics Covered

• Questions about race
• Fundamentals of DNA and the genome
• Human genome sequence
• DNA sequence variation
• Three essential features of human genome diversity
• Expected nucleotide diversity
• STR analysis
• Relationships among human populations
• Major long-range human migrations
• Definition of race
• Allocation of individuals to genetic clusters
• Principal pathway of ethanol metabolism
• Allele frequencies at ALDH2 locus
• European ancestry and diabetes risk

Links

Series:

• Evolution and Medicine

Categories:

• Clinical Practice
• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007
• Reviewed on August 16, 2020

Financial Disclosures

• Prof. Jeffrey Long has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.