Stem cell memory

Published on October 1, 2007 Updated on December 31, 2017   64 min

Other Talks in the Series: Epigenetics

Hello. My name is James L. Sherley. I am the Director of Asymmetrex.LLC located in Boston, Massachusetts in the United States. The topic of my presentation is Stem Cell Memory.
Part one of the presentation is: Defining stem cell memory.
I would like to begin with a brief discussion of the two main types of stem cells that are of interest for biomedicine and biotechnology. The first of these embryonic stem cells are derived from an early stage in development called the blastocyst. Within the blastocyst, there's an inner cell mass composed of cells called epiblast. When epiblast are placed in culture on appropriate conditions, they give rise to embryonic stem cells. There is much excitement over embryonic stem cells because each of these cells has the potential to give rise to all of the diverse cell types found in the mature body. The second type of stem cells, adult stem cells, occur late in fetal development at about the time that organs begin to form. As we will see, adult stem cells are found in most adult tissues.