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Biomedical Basics

Cellular signalling

  • Created by Henry Stewart Talks
Published on October 30, 2025   8 min

A selection of talks on Biochemistry

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The topic of Cellular Signalling will be explored through the fundamentals of how cells detect and transmit signals through various receptors and molecular pathways, enabling them to respond dynamically to environmental cues. We will examine key mechanisms like signal amplification, molecular switches, feedback regulation, and the integration of competing signals that control vital processes such as proliferation, differentiation, survival, and apoptosis. Examples will illustrate how disruptions in these networks contribute to diseases, and how modern research and therapies target these pathways. Ultimately, we highlight the core principles and medical relevance of cellular signalling in coordinating life at the molecular, cellular, and systems levels.. Cellular signalling is the intricate language underpinning life at the cellular level. Each cell senses its environment, relays information, and coordinates responses with nearby cells through signalling processes reacting to hormones, growth factors, cytokines, and neurotransmitters. The interplay of these signals directs cells to proliferate, differentiate, survive, or undergo programmed death. These precisely regulated, rapid transmissions ensure orchestrated responses to changing circumstances. The cellular language includes various types of signals, specific receptors, the complex machinery transmitting and amplifying responses, and the resulting effects on cell fate and function. Cells encounter signalling molecules—such as

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