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1. Introduction
2. East Carolina University (1)
3. East Carolina University (1)
4. East Carolina - industries
5. Obesity trends among U.S. adults
6. Obesity in East Carolina
7. Mortality due to diabetes
8. Regional convergence of social issues
9. The East Carolina medical facilities - before
10. The East Carolina medical facilities - after
11. Intensive care unit
12. The new heart hospital
13. Animal facilities
14. The new cardiac research building
15. The new college of nursing
16. East Carolina University (3)
17. 1978 - "let's research together"
18. Obesity as a common research (1)
19. Obesity as a common research (2)
20. Obesity: the most prevalent, fatal, chronic disease
21. Comorbidities in the severely obese
22. The intestinal bypass
23. The Mason and the Greenville gastric bypasses
24. The platinum rules of clinical research
25. The Greenvile gastric bypass
26. Weight loss 16 years after bariatric surgery
27. The bypass produces durable and safe weight loss
28. Enabling women to concieve
29. The weight loss is sustained
30. The Swedish obesity study results
31. The first surgeries on diabetic patients
32. Remission of diabetes after gastric bypass
33. Results from diabetics and IGT impaired patients
34. Mortality in obese patients
35. Long-term survival Canada
36. Unadjusted cumulative mortality: Swedish study
37. Operative changes in abdominal pressure
38. Bariatric surgery - urinary diary parameters
39. Bariatric surgery - effect on venus ulcers
40. Bariatric surgery - effect on sleep apnea
41. Pulmonary artery pressure before and after surgery
42. PaO(2) and PaCO(2) before and after surgery
43. Bariatric surgery - effect on other parameters
44. Example - Greg
45. Bariatric surgery - effect on CSF pressure
46. Health problems post-surgery
47. Five year comorbidity comparison
48. What is diabetes mellitus?
49. Insulin resistance in type 2 diabetes
50. Type 2 diabetes is due to failure of the islets
51. Oral glucose tolerance tests
52. Islets in type 2 diabetes
53. Islets in type 1 diabetes
54. What if the problem is overproduction of insulin?
55. Is the gut over stimulating the islets?
56. Response of insulin levels to the GGB
57. Other effects of insulin overproduction
58. The islets are stimulated by various factors (1)
59. Genetic leptin deficiency causes obesity in mice
60. Leptin receptor mutation causes obesity in mice
61. The islets are stimulated by various factors (2)
62. The insulin receptor and signal transduction
63. Insulin sensitivity in non-diabetic bypass patients
64. Muscle IRS1 serine phosphorylation post-surgery
65. Insulin secretion pre and post GGB
66. Improvement in insulin resistance post GGB
67. GGB effect on GLP-1 levels
68. GLP-1 in response to a meal in non-diabetics
69. The complexity of the insulin production
70. Different types of bariatric surgeries
71. Comparison of bariatric surgeries' efficiency
72. Is the remission due to weight loss alone?
73. Rubino studies on GK rats
74. Duodenal-jejunal bypass (DJB) in the GK rat
75. Duodenal exclusion in the diabetic non-obese rat
76. OGTT after duodenal exclusion
77. Duodenal silastic tube
78. Insulin sensitivity in non-diabetic GB patients
79. Studies in non-obese diabetic patients
80. DJB effect on lean diabetic patients - weight
81. DJB effect on lean diabetic patients - HbA1c
82. 6 months follow up DJB in lean diabetic patients
83. Gastrectomy and diabetes - 1955
84. Indications for bariatric surgery
85. Which operation is best?
86. The risks in bariatric surgery
87. Mortality due to bariatric surgery
88. Mortality due to other surgeries
89. Conclusions

Topics Covered

• Eastern North Carolina: an epidemiologic laboratory
• The Development of the gastric bypass
• Health effects of the gastric bypass
• Potential mechanisms of action
• Safety issues

Links

Series:

• Obesity

Categories:

• Clinical Practice
• Metabolism & Nutrition

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Pories, W. (2009, April 30). Bariatric surgery: techniques and mechanisms of action [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/WYED4036.
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Publication History

• Published on April 30, 2009
• Archived on February 25, 2021

Financial Disclosures

• Prof. Walter Pories has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.