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- Epidemiology
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2. Epidemiology of obesity
- Prof. Jacob Seidell
- Etiology and Causes
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3. Metabolic, adipose tissue and muscle predictors of obesity
- Prof. Ian Macdonald
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4. Neural control of food intake and energy balance
- Prof. Hans-Rudolf Berthoud
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6. Dietary determinants of obesity
- Prof. Arne Astrup
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7. Physical inactivity as a determinant of obesity
- Prof. Wim Saris
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8. Environmental causes of obesity: sociocultural, built environment and economic factors
- Prof. Shiriki Kumanyika
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9. The developmental origins of obesity
- Prof. David Barker
- Consequences of Obesity
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10. Obesity, dyslipoproteinemia and inflammation
- Prof. Robert Eckel
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11. Pathophysiology and management of obesity related hypertension
- Prof. Arya Sharma
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12. Disorders of overeating
- Prof. Albert Stunkard
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13. Obesity, weight loss and health-related quality of life
- Prof. Aila Rissanen
- Dr. Jarmo Kaukua
- Treatment Options
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14. Lifestyle modification for weight control
- Prof. Thomas Wadden
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15. Bariatric / obesity surgery
- Prof. Henry Buchwald
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16. Can obesity be prevented in the current obesogenic environment?
- Prof. Boyd Swinburn
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17. Pharmacotherapy for obesity: why it is needed
- Prof. Joe Proietto
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18. Pharmacotherapy for obesity: hunger suppressors
- Prof. Joe Proietto
- Latest Developments in the Field
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19. Body composition
- Dr. Steven Heymsfield
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20. Adipose tissue metabolism and obesity
- Dr. Max Lafontan
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21. Obesity, present and future therapies
- Prof. Sir Stephen Bloom
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22. Energy expenditure in the lean and obese
- Prof. Dale Schoeller
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23. Obesity and adiponectin
- Prof. Philipp Scherer
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24. Ectopic fat: causes, consequences and treatment
- Prof. Steven Smith
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25. Adipose-immune interactions in obesity
- Dr. Vishwa Dixit
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26. Health benefits of intentional weight loss
- Prof. Xavier Pi-Sunyer
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27. Childhood obesity: implications for current and future health
- Prof. Peter T. Katzmarzyk
- Archived Lectures - These lectures may not cover the latest advances in the field
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29. Gastrointestinal peptides and food intake regulation
- Prof. Sir Stephen Bloom
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30. Obesity and mortality: questions and controversy
- Prof. David Allison
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31. Obesity, diabetes and the cluster of the metabolic syndrome
- Prof. Peter Wilson
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33. Health economics of obesity: new insights
- Dr. Anne Wolf
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34. Bariatric surgery: techniques and mechanisms of action
- Prof. Walter Pories
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35. Childhood obesity: implications for future health
- Prof. Peter T. Katzmarzyk
Printable Handouts
Navigable Slide Index
- Introduction
- Global prevalance of obesity
- Current and coming anti-obesity agents
- Bariatric surgery - the only successful therapy
- Skin redundancy after massive weight loss
- The gut hormones
- Ghrelin
- Energy intake after administration of ghrelin
- Meal intake after ghrelin infusion in cancer patients
- Why do you feel less hungry after a meal?
- Gut hormones: three types of satiety action
- Peptide YY (PYY) (1)
- GI tract distribution of PYY
- Post prandial secretion of PYY
- Peptide YY (PYY) (2)
- PYY levels in different patients
- PYY levels elevated post bypass surgery
- Effect of PYY3-36 on food intake (1)
- Effect of PYY3-36 on food intake (2)
- Effect of PYY3-36 on cumulative 24h food intake
- PYY3-36 hunger scores
- PYY3-36 on ghrelin
- PYY levels during saline infusion
- Meal calories and PYY blood level in fat and thin
- Plasma PYY levels at each infusion dose
- Percent reduction in calories after PYY infusion
- Food intake increased after PYY
- Three characteristics of PYY3-36 on appetite
- Glucagon-like peptide 1
- The effect of chronic GLP-1 on body weight
- Exendin stimulates food intake in satiated rats
- 24 week trial of exenatide against insulin glargine
- 82 weeks follow up
- Oxyntomodulin (1)
- Oxyntomodulin (2)
- Chronic IP administration of oxyntomodulin
- Effect of oxyntomodulin on food intake in humans
- Four week oxyntomodulin trial
- Trial protocol
- Type of administration
- Oxyntomodulin effect on weight loss
- Oxyntomodulin effect on leptin levels
- Oxyntomodulin effect on calorie intake
- Oxyntomodulin effect on insulin levels
- Effect on energy expenditure
- Oxyntomodulin and energy balance
- Design of oxyntomodulin analogues
- Oxyntomodulin analogue 23/36
- Effect of oxyntomodulin analogue on weight loss
- Oxyntomodulin versus GLP-1
- Manganese enhanced MRI
- Ghrelin manganese enhanced MRI
- GLP1 against oxyntomodulin
- Buffet meal energy intake
- Human pancreatic polypeptide (1)
- Human pancreatic polypeptide (2)
- Effect of hPP analogues on food intake
- Effect of PYY, hPP or combination on food intake
- Peptides as drugs - better targeted
- Rimonabant and oxyntomodulin are additive
- Concluding remarks
Topics Covered
- Anti-obesity agents
- Bariatric surgery
- The gut hormones
- Ghrelin
- Energy intake free-choice meal
- Meal intake after Ghrelin infusion
- Why do you feel less hungry after a meal?
- Three types of satiety action
- Peptide YY (PYY)
- GI tract distribution of PYY
- Post-prandial secretion of PYY
- Effect of PYY on food intake
- Glucagon-like peptide 1
- The effect of chronic GLP-1 on body weight
- Oxyntomodulin
- Leptin change
- Human pancreatic polypeptide
- Peptides as drugs: better targeted
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Bloom, S. (2009, March 31). Gastrointestinal peptides and food intake regulation [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved March 21, 2025, from https://doi.org/10.69645/OJXA9457.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Sir Stephen Bloom, Grant/Research Support (Principal Investigator): Medical Research Council