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1. Introduction
2. Drugs used in pain management (1)
3. Drugs used in pain management (2)
4. Route of drug administration
5. How to choose the right analgesic
6. Acute pain
7. Mechanism based
8. Nociceptive vs. neuropathic pain
9. Cancer pain
10. WHO ladder for cancer pain
11. Modified WHO ladder for cancer pain
12. Absorption of fentanyl through the skin
13. Evidence-based pain relief
14. Comparison of different analgesics (1)
15. Comparison of different analgesics (2)
16. Interindividual variation of PTGS1 and PTGS2
17. PTGS2 polymorphisms and analgesic response
18. Interindividual variation in response to codeine
19. Pharmacokinetics of codeine and morphine
20. Tramadol
21. Pharmacogenetics of analgesics
22. Human mu opioid receptor gene SNPs
23. NSAIDS & COXIBs
24. Adverse effects of NSAIDs
25. Endogenous opiates and behavior
26. Nomenclature of opioid receptors
27. Opioid receptor binding and activation
28. Morphine and oxycodone in the brain and plasma
29. Log octanol/water partition coefficients of opioids
30. Pharmacokinetics of opioids (1)
31. Transfer half-lives of opioids - plasma and brain
32. Important half-lives of opioids
33. Pharmacokinetics of opioids (2)
34. Metabolism of oxycodone
35. Oxycodone: CYP 3A4
36. SEM plasma concentrations after oxycodone
37. Equianalgesic doses
38. Pharmacokinetics of methadone
39. Elimination of methadone
40. Methadone drug interactions
41. Adverse effects of opioids
42. Neuropathic pain
43. Blocking sodium channels
44. Treatment of neuropathic pain: Evidence of efficacy
45. Antidepressants
46. Neuropathic pain conditions: Antidepressants
47. Mechanisms of action of antidepressants
48. Drug interactions
49. Ca++-channel modifiers as analgesics
50. Gabapentinoids mechanism of action
51. Gabapentinoids effects
52. Neuropathic pain conditions: Gabapentinoids
53. Sodium channel blockers as analgesics
54. Mechanisms of action of anticonvulsants
55. Topical analgesics
56. Capsaicin
57. New indications for "adjuvant" drugs
58. Opioids in chronic non-cancer related pain (1)
59. Opioids in chronic non-cancer related pain (2)
60. Treatment duration
61. Adverse effects
62. Other concerns
63. Combinations
64. Tailoring treatment for the individual patient
65. New targets
66. Guidelines

Topics Covered

• Drugs used in pain management
• Drug administration
• Choosing the right analgesic
• Cancer pain
• Modified WHO ladder
• Opioid medication
• Inter-individual variation
• Pharmacokinetics and pharmacogenetics
• Adverse effects
• Half-lives of opioids
• Drug interactions
• How to treat adverse effects
• Neuropathic pain
• Anti-depressants
• Topical analgesics
• Adjuvant drugs
• Non-cancer pain
• Combinations of drugs
• New targets
• Guidelines

Links

Series:

• Pain and the Control of Pain

Categories:

• Clinical Practice
• Neuroscience
• Pharmaceutical Sciences

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on February 25, 2010

Financial Disclosures

• Prof. Eija Kalso has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.