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1. Introduction
2. Primary dyslipidemias
3. Structure of lipoproteins
4. Physicochemical properties of lipoproteins
5. Lipoprotein classes and atherosclerosis
6. Autosomal dominant hypercholesterolemia
7. Autosomal recessive hypercholesterolemia
8. Primary dyslipidemias
9. Familial hypercholesterolemia pedigree
10. Metabolic abnormality in FH
11. The attribute of sex to coronary death
12. Typical xanthomas
13. Atherosclerosis recognition by Bmode ultrasound
14. Thin intima vs. thick intima
15. Diagnosis of FH
16. Pharmacotherapy
17. Mechanism of action of statins
18. Increase in the synthesis of hepatic LDL receptors
19. Niacin
20. Dual inhibition
21. Hypolipidemic drug therapy
22. Case FH
23. Case FH: LDL-c lowering after combined treatment
24. FH - current situation
25. Tracing FH patients
26. Familial combined hyperlipidemia
27. FCH prevalence
28. 1973 FCH definition
29. FCH pedigree
30. Lipid and lipoprotein levels in FCH
31. Lipoprotein particle size
32. Associated CHD risk with an apoB increase
33. Insulin resistance in FCH
34. Values for prediction of FCH
35. Therapy FCH
36. Hypertriglyceridemia treatment
37. Familial hypertriglyceridemia
38. TG levels after treatment
39. TG concentration and production
40. Triglycerides variation in serum
41. Cholesterol and triglycerides elevated
42. Familial dysbetalipoproteienemia
43. Palmar streaks in FD
44. Tubero eruptive xanthomas in FD
45. Apolipoprotein E isoforms
46. Pedigree of index-patient and family members
47. ApoE type and frequencies in the Netherlands
48. Cholesterol levels in apoE2/E2
49. Aggravating factors
50. Lipid values in FD patients
51. Reduced penetrance
52. Clinical diagnosis
53. Secondary dyslipidemias
54. Secondary forms of HLP
55. Lipemia retinalis
56. Appearance of plasma before and after treatment

Topics Covered

• Primary dyslipidemias
• Autosomal dominant and recessive hypercholesterolemia
• Familial hypercholesterolemia
• Familial combined hyperlipidemia
• Familial hypertriglyceridemia
• Familial dysbetalipoproteinemia
• Pharmacotherapy
• Secondary dyslipidemias

Links

Series:

• Genetics of Cardiovascular Disease

Categories:

• Clinical Practice

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Publication History

• Published on November 24, 2008

Financial Disclosures

• Prof. Anton Stalenhoef has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.