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1. Introduction
2. Lipids
3. Functions of lipids
4. Outline (1)
5. Lipid absorption in the intestine
6. Intestinal sterol uptake
7. Intestinal fatty acid uptake
8. Intestinal chylomicron formation
9. Postprandial hyperlipidemia
10. Lipoprotein model
11. Major lipoproteins and apoproteins
12. Apo B100 and Apo B48 are derived from one gene
13. Postprandial lipoprotein metabolism
14. Insulin as a major postprandial hormone
15. Metabolism of adipose tissue
16. Nutritional lipids are also delivered to the bone
17. CR deliver lipids and vitamin K to the bone
18. Outline (2)
19. Hepatic lipid metabolism
20. Hepatic receptors for lipoprotein uptake
21. CR uptake into the liver
22. Hepatic lipoprotein pathways
23. Size of VLDL determines LDL size
24. Role of apo E in lipoprotein catabolism
25. Apo E polymorphism
26. Outline (3)
27. LDL receptor a key player in cellular homeostasis
28. Intracellular cholesterol regulated gene expression
29. Outline (4)
30. Reverse cholesterol transport by HDL
31. Lipid exchange proteins
32. Normal levels for plasmalipids
33. Dietary lipids
34. Thank you

Topics Covered

• Functions of lipids
• Lipid absorption in the intestine
• Intestinal sterol and fatty acid uptake
• Intestinal chylomicron formation
• Postprandial hyperlipidemia
• Lipoprotein model
• Major lipoproteins and apoproteins
• Postprandial lipoprotein metabolism
• Insulin as major postprandial hormone
• Metabolism of adipose tissue
• Nutritional lipids are also delivered to the bone
• Chylomicron remnants deliver lipids and vitamin K to the bone
• Hepatic lipid metabolism
• What are the receptors responsible for CR uptake?
• CR uptake into the liver
• Hepatic lipoprotein pathways
• Size of VLDL determines LDL size
• Role of apo E in lipoprotein catabolism
• Apo E polymorphism
• Cellular cholesterol homeostasis
• LDL receptor involved in cellular cholesterol homeostasis
• Intracellular cholesterol regulated gene expression
• 'Reverse cholesterol transport' by HDL
• Lipid exchange proteins
• Normal levels for plasmalipids
• Dietary lipids

Links

Series:

• Genetics of Cardiovascular Disease

Categories:

• Clinical Practice

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Publication History

• Published on December 15, 2008
• Archived on August 5, 2024

Financial Disclosures

• Dr. Ulrike Beisiegel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.