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              Printable Handouts
Navigable Slide Index
Topics Covered
- Neurodegenerative disease: the medical imperative for the developed world
- Neurodegeneration is a major health care crisis
- Ages of neurodegenerative disease research
- Clinicopathological description
- Transmitter biochemistry
- Genetic analysis of causation
- Disease genes for all the major disorders
- The future
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Talk Citation
Hardy, J. (2014, August 5). Neurodegenerative disease: the medical imperative for the developed world [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 31, 2025, from https://doi.org/10.69645/HVBE1055.Export Citation (RIS)
Publication History
- Published on August 5, 2014
Financial Disclosures
- Prof. John Hardy, Consultant: Eisai Speaker's Bureau: Eli Lily Grant/Research Support (Principal Investiqator): MRC/Wellcome Trust
Neurodegenerative disease: the medical imperative for the developed world
                  Published on August 5, 2014
                  
                    
                      
                        
                      
                    
                  
                  
                    13 min
                
              A selection of talks on Neuroscience
Transcript
Please wait while the transcript is being prepared...
      
      
        
                  0:00
                
                
                  
                    Hello, my name's John Hardy.
                  
                    And together with my
colleague, Patrick Lewis,
                  
                    I've been responsible
for putting together
                  
                    the series of talks
which are in this series.
                  
                    And I just thought it would
be worth spending some time
                  
                    to put this series into a
kind of historical perspective
                  
                    and explain why it's important,
what the history of research
                  
                    in this area has been,
and in the final slide,
                  
                    perhaps talk a little
bit about where
                  
                    I think the future is for
this type of research.
                  
                
              
                  0:35
                
                
                  
                    Neurodegenerative diseases are
really the major health care
                  
                    problem in the developed world now.
                  
                    And I say the developed world,
but in fact, life expectancy
                  
                    is increasing in the developing
world to an enormous extent,
                  
                    as well.
                  
                    And so we can see that this is a
problem which is going to be all
                  
                    over the world over the next period.
                  
                    The numbers are staggering.
                  
                    Alzheimer's disease affects
1% at the age of 60, 20%
                  
                    at the age of 80.
                  
                    Parkinson's disease affects
1% over the age of 60.
                  
                    The other diseases are rarer, but
altogether, probably affect about 1%
                  
                    of the population.
                  
                    And this means that in a
population of 50 million,
                  
                    about 1.5 million will
be directly affected-- that means
                  
                    diagnosed-- with one
of these diseases.
                  
                    Of course, when I say 1.5 million directly affected,
                  
                    each one of them will have relatives
who are indirectly affected.
                  
                    There will be caregivers and
spouses and children and so on.
                  
                    So indirectly affected will
be a far larger number.
                  
                    And of course, as the population
ages-- all of these diseases
                  
                    are age-related diseases--
this number will increase.
                  
                
              
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