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0:00
Hello, everyone. My name
is Dr. Sarah Fouch.
Welcome to this short
recording where we
will be considering
Bordetella pertussis.
We will discuss the
clinical condition
most associated
with this organism
and the virulence
factors that it
produces to make it a
successful pathogen.
0:22
So, let's think
about Bordetella.
These are small organisms.
We call them coccobacilli, but
actually they are
gram-negative bacilli.
They look like cocci
because they are so short.
We need specific media
to grow these organisms,
and media such as
Bordet-Gengou or
Regan-Lowe agar can
provide all of the requirements
that these organisms need.
If we isolate
Bordetella pertussis
on Bordet-Gengou media,
they produce nice pearly
transparent colonies.
Let's think about
the specific media.
Now, these media
contain charcoal,
starch, a range of
antibiotics, and also blood.
As I said previously,
all of these elements are
essential for optimal growth.
Now, blood is included to
detect haemolytic patterns.
Antibiotics are
included to remove
any normal flora within
the patient's sample.
Starch is incorporated to
absorb any fatty acids present
within nasal secretions
because these
could potentially inhibit
the growth of the organism.
Now, the clinical
condition associated with
Bordetella pertussis
is whooping cough.
When we think about
other species of
