Printable Handouts

PDF

Navigable Slide Index

1. Sulfation & human cytosolic SULTs
2. Sulfation or sulfonation
3. Obligate sulfonate donor
4. PAPS synthesis/transport
5. Sulfation kinetics & drug metabolism
6. Sulfation kinetics - subst. inhibition
7. SULT reaction mechanism
8. Human SULT families
9. Human cytosolic SULTs
10. Human SULT gene location
11. Human SULT1A gene family
12. Human platelet phenol SULTs
13. SULT1A1
14. SULT1A1 pharmacogenetics
15. SULT1A3
16. SULT1B1
17. SULT1C isoforms
18. Human SULT1E1
19. Inhibition of SULT1E1 by E2
20. Activity of human SULT1E1
21. Reactions of human SULT1E1
22. Ligand binding stoichiometry - hEST
23. Binding sites for pNP1 in SULT1A1
24. SULT1E1 expression and function
25. Human SULT2A1
26. DHEA-sulfate plasma levels
27. SULT2A1 in reticular layer
28. Human steroid metabolism
29. SULT2A1 - sulfation of steroids
30. Human SULT2A1 polymorphism
31. Human SULT2B1 isoforms
32. SULT2B1b, SULT2B1a, SULT2A1
33. Analysis of SULT2B1 isoforms
34. Sulfation in MCF-7 cells/cytosol
35. Localization of SULT2B1b (1)
36. Localization of SULT2B1b (2)
37. Immunolocalization of SULT2B1b
38. SULT4A1 - brain selective SULT
39. Bioactivation and sulfation
40. Compounds activated via sulfo. - ex.
41. Mutagen activation by human SULTs
42. Mutagen activation by SULT1B1
43. Summary
44. References (1)
45. References (2)
46. References (3)
47. References (4)
48. References (5)

Topics Covered

• Cytosolic sulfotransferase (SULTs) gene family
• Physiological and pharmacological activity
• Xenobiotic and drug conjugation
• Substrate specificities
• Major groups SULT1 and SULT2
• Tissue-specific expression and regulation

Links

Series:

• Drug Metabolizing Enzymes

Categories:

• Biochemistry
• Pharmaceutical Sciences

Talk Citation

Falany, C. (2007, October 1). Sulfation and human cytosolic sulfotransferases [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 21, 2024, from https://doi.org/10.69645/QCXR5679.
Export Citation (RIS)

Publication History

• Published on October 1, 2007
• Archived on October 25, 2018

Financial Disclosures

• Prof. Charles Falany has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.