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Diagnosis of tuberculosis and drug resistant tuberculosis 1

Part 1 of 2
Published on July 31, 2025   29 min

A selection of talks on Immunology

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0:00
Good morning. My name is Daniela Cirillo. I work at the San Raffaele Scientific Institute in Milano, where I'm leading a WHO collaborating center in tuberculosis laboratory strengthening. The topic of today is the diagnosis of tuberculosis and drug-resistant tuberculosis.
0:23
Briefly, my outline will touch on the introduction of tuberculosis, the guidelines for the diagnosis of tuberculosis that have been very recently issued by the WHO, the role of WGS and the targeted NGS, and the mechanism of resistance with particular attention to the new drugs, and what the new perspective is for the future. Of course, this presentation reflects my personal view, not the view of the WHO or any of the organizations I'm collaborating with.
1:01
The Global Report 2023 underlines three very important aspects compared to the past years. The first one is that there was a major global recovery in the number of people diagnosed with TB and treated in 2022 after two years of COVID-related disruption. This started to reverse or moderate the damaging impact of the pandemic on the diagnosis and treatment of people with tuberculosis. However, tuberculosis remains the world's second leading cause of death from a single infectious agent in 2022.

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Diagnosis of tuberculosis and drug resistant tuberculosis 1

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