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Printable Handouts
Navigable Slide Index
- Introduction
- Learning goals: what are “the genetics of adaptation”?
- What shapes biological diversity?
- What is adaptation?
- Adaptation example 1 - light and dark morphs of the peppered moth
- Adaptation example 2 - antimicrobial resistance
- Adaptation example 3 - lactose intolerance
- Adaptation example 4 - horned lizards shoot blood out of their eyes
- Adaptation example 5 - male peacock spider dance
- What are the “genetics of adaptation”?
- Genotype and phenotype
- Genotype, phenotype and environment
- The development of the genetics of adaptation
- Mapping the technological developments in the field
- Learning goals: what is a real-life example?
- The arc of a career
- Adaptation in nature - the evolution of color
- Adaptation in nature - white sands desert
- Adaptation in nature - white lizards
- Conditions for adaptation
- Studying adaptation in nature
- Studying the genetics of adaptation
- The melanocortin 1 receptor gene
- Can we see evidence for selection in the genome?
- Studying selection in the genome
- The genetics of adaptation (and speciation) (1)
- The genetics of adaptation (and speciation) (2)
- The genetics of convergent and parallel adaptation
- The genetics of convergent and parallel adaptation - different phenotypes of lizards
- The genetics of convergent and parallel adaptation - melanism in pocket mice
- The genetics of convergent and parallel adaptation - coat color in woolly mammoth
- The genetics of convergent and parallel adaptation - genetic tools
- Learning goals: what are the key questions for the future?
- Connecting genotype to phenotype (1)
- The power of comparison
- Connecting genotype to phenotype (2)
- New fields and false dichotomies (1)
- Coding or regulatory mutation?
- Few loci of large effect or many loci of small effect (1)
- Few loci of large effect or many loci of small effect (2)
- Standing genetic variation or new mutation
- New fields and false dichotomies (2)
- What shapes biological diversity?
- Learning goals
- Acknowledgements
Topics Covered
- Biological diversity
- Adaptation Examples of adaptation
- Genetics of adaptation
- Adaptation in nature
- Conditions for adaptation
- Melanocortin 1 receptor gene
- Convergent and parallel adaptation
Links
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Therapeutic Areas:
Talk Citation
Rosenblum, E.B. (2025, April 30). The genetics of adaptation [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 3, 2025, from https://doi.org/10.69645/JGXN8261.Export Citation (RIS)
Publication History
- Published on April 30, 2025
Financial Disclosures
- Prof. Erica Bree Rosenblum has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: Introduction to Evolutionary Biology
Transcript
Please wait while the transcript is being prepared...
0:00
Welcome. My name
is Bree Rosenblum.
I am a professor at the University
of California, Berkeley,
and today, I'm excited
to share a topic
that is near and
dear to my heart,
on the genetics of adaptation.
0:13
Today, I'd like to accomplish
three things with you.
First, I want you to
understand what do I mean
when I say "the genetics
of adaptation."
Second, I'd like to walk through
a real-life example with you
that's based on my own research.
Third, I'd like to make
sure you understand
the importance of this field
and what are the
pressing questions
that we need to
answer in the future.
Let's get started.
What are the genetics
of adaptation?
0:36
Well, as you know, our
world is comprised of
an incredible amount of
biological diversity,
and that biological
diversity has evolved over
millions and millions
and millions of years.
There are a few major
processes in evolution
that shape biological diversity,
that shape the tree of life.
In some of the introductory
lectures about evolution,
you've probably heard
about genetic drift
and natural selection.
Today, we're really going to
zoom in on natural selection.
Natural selection is one
of the primary processes
that shape life on Earth.
1:08
What is natural selection?
Well, let's talk
about adaptation.
Adaptation is the result
of natural selection.
It's the process by which
organisms become better suited to
the environmental conditions
where they're found,
and it's important
to remember that
this adaptation is
occurring based on
heritable genetic changes
over generations.
Adaptation isn't just how
individual organisms
change in response,
moment to moment, to
their environments.
Adaptation is the process of
organisms becoming suited,
over generations,
with genetic changes.
In order for adaptation by
natural selection to proceed,
we need to have variation
in a population.
Not all individuals
can be the same.
We need to have heredity,
a way for those traits to be
passed across generations,
from parents to offspring,
and we need to have
differences in survival
or reproduction.
There has to be a reason why
some individuals are better
suited to the environment
and more likely to
pass their genes on
to the next generation.
Adaptation is occurring
all the time around us,
and I'm going to
take a deeper dive
into a specific example,
but first I just want to
highlight a handful of examples.