Please wait while the transcript is being prepared...
0:00
Hello, I'm Dr. Sheetal Parida.
I'm a researcher at the Johns
Hopkins School of Medicine.
I work on the role of microbiome
in cancer development,
specifically breast
cancer. This talk,
I'm going to briefly discuss
the role of gut
microbiome in general
and other specific
microbiome and
development and
progression of cancers.
0:23
The topics I will be covering in
this talk would be
what's the microbiome?
where is the human
microbiome located?
Why is the human
microbiome important?
How do we study the
human microbiome?
Which are the diseases impacted
by the human microbiome?
Does the microbiome impact
cancer risk? If so, how?
The potential mechanism of
microbiome's role in cancer
initiation and progression.
The role of microbiome in
breast cancer initiation
and progression.
How can the microbiome
be manipulated or
exploited for the cancer
patients benefit.
The efforts currently
underway and
some further reading material.
0:59
So to start with,
I would go to the
definition of microbiome,
which is a community of
microorganisms that exist in
a particular environment.
In humans, the term is
often used to describe
the microorganisms that live in
or on a particular
part of the body,
such as the skin or GI tract,
and these groups
of microorganisms,
some are dynamic and change in
response to host environmental
factors like exercise,
diet, medication,
other exposures
like pollutants, radiation, etc.
The human microbiome is
composed of archaea,
bacteria, viruses, and fungi.
Here we are going
to specifically
discuss about bacteria
because that's the
most widely studied of the
52 phyla found on earth,
the human gut microbiome
consists of eight phyla,
18 families, 23 classes,
38 orders, 59
genera, 109 species,
and the majority of it is
composed of three phyla,
firmicutes, actinobacteria,
and bacteroidetes.
