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Printable Handouts
Navigable Slide Index
- Introduction
- Talk outline
- Biological and sociologic concepts of sex and gender
- Aspects of sex and gender in humans
- Sex differentiation: genetic aspects
- Sex differentiation: anatomic & physiologic aspects
- Sex differentiation: undifferentiated stage
- Sex differentiation: gonadal differentiation
- Sex differentiation: genital differentiation
- Genital differentiation: anatomic details
- Intersex conditions = disorders of sex development (DSD)
- Etio-pathogenic classification: malformative
- Etio-pathogenic classification: dysgenetic
- Dysgenetic: complete or partial testicular dysgenesis
- Dysgenetic: ovotestes
- Ovotesticular DSD / SRY(-)
- Dysgenetic: complete or partial ovarian dysgenesis
- Etio-pathogenic classification: non-dysgenetic (XY)
- Non-dysgenetic (XY): isolated androgen synthesis
- Non-dysgenetic (XY): isolated AMH synthesis
- Etio-pathogenic classification: non-dysgenetic (XX)
- Non-dysgenetic (XX)
- Non-dysgenetic (XX): congenital adrenal hyperplasia
- Congenital adrenal hyperplasia (CAH)
- Disorders (differences) of sex development
- Aromatase deficiency
- Hyperandrogenic states in pregnancy
- DSD: management (1)
- DSD: management (2)
- Take home messages
- Thank you for your attention!
Topics Covered
- Concepts of sex and gender
- Biologic aspects of sex
- Chromosomal sex
- Genetic sex
- Gonadal sex
- Etio-pathogenic classification
- Dysgenesis
- AMH (Anti Mullerian Hormone)
- DSD (Disorders of Sex Development) management
- Congenital adrenal hyperplasia (CAH)
Links
Categories:
Therapeutic Areas:
Talk Citation
Rey, R. (2023, February 28). Intersex conditions / disorders of sex development [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 16, 2024, from https://doi.org/10.69645/RITD7735.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Rodolfo Rey has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Intersex conditions / disorders of sex development
Published on February 28, 2023
28 min
A selection of talks on Reproduction & Development
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is Rodolfo Rey,
I'm a physician and
a researcher of
the CONICET the National
Research Council of Argentina at
the Center for
Endocrine Research at
the Buenos Aires
Children's Hospital
and we will discuss today
intersects conditions
or disorders of
sex development so this
is the talk outline.
0:24
I will start by a
brief introduction on
the biological and
sociological concepts
of sex and gender.
To then address the
biological aspects of
fetal sex differentiation
and devote most of
the talk to intersex
conditions or disorders of
sex development
that some authors
like to call differences
of sex development.
0:53
Sex refers to the biological
aspects of an individuals,
for example ovaries are the
female gonads while testes,
are the male gonads,
estrogens are predominantly
female hormones,
whereas androgens are
predominantly male hormones.
Whereas gender as a more
psycho-social meaning and
refers to the self-perception of
an individual as a
male or a female,
non-binary or other
possibilities,
and also to the
perception of others.
That is the gender role in
society so when we talk
about sex and gender,
1:34
we can address it from
different aspects.
The genetic aspect, that is
the chromosomal and genetic sex
that will influence
the anatomic and
physiological aspects.
That is the gonadal
sex, genital sex,
and also the sex of
other organs that are
not as dimorphic as the
gonads or the genitalia,
but shows some
differences between
sexes and then the
cycle social aspects,
that is the legal gender
or sex assignment.
The gender of rearing,
gender role behavior
or expression,
gender identity and
sexual orientation.
I will not refer to the
psychosocial aspects,
but we'll concentrate
on the genetic aspects
and anatomic and physiological
aspects of sex in
this talk so when referring to