Routes of drug delivery

Published on June 29, 2022   29 min

A selection of talks on Pharmaceutical Sciences

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Ladies and gentlemen, my name is Sven Stegemann. I'm from the Graz University of Technology, Institute of Process and Particle Engineering in Graz, Austria. I will give you an introduction to the routes of drug delivery.
You see the definition. We'll talk about the route of drug delivery as a combination of routes of administration and drug delivery. The route of administration is basically the path by which a drug molecule, biologic or any other substance, is taken into the body or the site of action. Drug delivery is a path by which this active is released in terms of rate, time, place in the body, in a very controlled or desired way.
You see the routes of administration, which we can basically classify into six major routes of administration. The first is the oral (enteral) route, which is going through the mouth. The parenteral route, mainly includes injection or infusion, which is injecting by a system of a needle directly into the body, through the arteries, into the veins, into muscle tissue. The next route of administration is the cutaneous (transdermal) route, everything which is going on or through our external skin. Pulmonary and nasal delivery is through our respiratory tract, either directly to the lung or our nose. The mucosal route is when we apply drug systems to any mucosa, which is basically a wet membrane that we have in our mouth, in the vagina and so on. The last one is really the emerging routes of drug administration, which is through advanced therapy, cell therapies, CAR-T cells, and so on.