Biobanks and their role in biomedical research

Published on June 29, 2022   36 min

A selection of talks on Pharmaceutical Sciences

0:00
Hi, everyone. I'm Elvira Mambetisaeva, a lecturer at the Division of Biosciences at University College, London. Welcome to this lecture on the introduction to biobanks and their role in biomedical research.
0:16
The aim of this lecture is to give you an overview of biobanking and to discuss how biobanks are supporting and advancing biomedical research. I will give you examples of different types of biobanks and I will mention studies in different areas of biomedical science that have been possible to do using samples and data from biobanks.
0:38
Biobanks or biorepositories are facilities, we also call them research repositories, that collect process, store, annotate and analyse specimens mainly for research. While biological sample collections from other living organisms can also be called biobanks, many researchers prefer to use the term biobank only for facilities that collect human biological samples. However, in the literature you will find out that both terms, biobank and biorepository, are used interchangeably. In this lecture, I will be focusing on human-derived biological samples.
1:19
Biobanks consist of two different parts. The first part is the biological material that is collected, processed and stored for a long time. The second part is the information that is associated with each biological sample. Biobanking is required in the recruitment of donors of biological samples. Biobanks collect samples from healthy people and all people with certain diseases and medical conditions. Biospecimen types that are available include: organ tissue, blood, saliva, urine, DNA and RNA extracted from different tissues, biopsies from tumours, different body fluids and other human tissues. Each sample is registered in the computer-based system and kept in the appropriate condition to preserve it. The physical location of the specific sample is also registered to enable the specimen to be easily located when they are required to be distributed to scientists for their approved research projects. Researchers gather molecular data from human biospecimens to gain greater insight into the genetic and molecular basis of diseases. To provide the context for biological samples,
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Biobanks and their role in biomedical research

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