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26 min
1. Planning and response to COVID-19: lessons from China and South-East Asia- Prof. Annelies Wilder-Smith
- 2022
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12 min
2. The emergence of the SARS-CoV-2 Omicron variant- Prof. Emma Thomson
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14 min
3. How is Omicron different?- Prof. Emma Thomson
- 2021
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14 min
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15 min
5. Potential of ‘long-COVID’ in triggering chronic co-pathologies- Dr. İmdat Eroğlu
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8 min
6. SARS-CoV-2 monoclonal antibody testing in vivo- Prof. Michael Diamond
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17 min
7. mRNA COVID-19 vaccine efficacy in recovered vs COVID-naive individuals- Prof. E. John Wherry
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12 min
8. SARS-CoV-2 variants: implications for immunity and vaccine development- Prof. Danny Altmann
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14 min
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11 min
10. SARS-COV-2 human monoclonal antibody therapy update- Prof. James Crowe
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12 min
11. Emergence of blood clotting disorders resulting from COVID vaccines inoculations- Prof. Dr. Sabine Eichinger
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9 min
12. SARS-CoV-2 evolution within and between individuals- Prof. Katia Koelle
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10 min
13. Identifying SARS-CoV-2 proteases- Prof. Dr. Christa E. Müller
- Prof. Dr. Michael Gütschow
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20 min
14. Genetic surveillance and the emergence of SARS-CoV-2 variants- Prof. Emma Thomson
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16 min
15. The COVID-19 outbreak: April 2021 update- Prof. Jonathan Temte
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15 min
16. ABO blood groups and SARS-CoV-2 susceptibility- Dr. Sean Stowell
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20 min
17. Impact of COVID-19 on neuropsychiatric disorders and mental health- Prof. Anthony David
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20 min
18. The immune system response to the SARS-CoV-2 virus: March 2021 update- Prof. Paul Klenerman
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6 min
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12 min
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13 min
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18 min
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17 min
23. SARS-CoV-2 vaccine rollout campaigns- Prof. Luis Graca
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11 min
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15 min
25. Interspecies transmission of SARS-CoV-2- Dr. Dalan Bailey
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12 min
26. Complement activation in COVID-19- Prof. Jeffrey Laurence
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9 min
27. Human movement patterns and local spread of COVID-19- Prof. Ben Cowling
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10 min
28. SARS-CoV-2 mutations: phenotypes and implications for vaccine development- Prof. David Montefiori
- 2020
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18 min
29. The immune system response to the SARS-CoV-2 virus: December 2020 update- Prof. Paul Klenerman
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20 min
30. Triage and end of life care planning in COVID-19- Prof. Robin Taylor
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14 min
31. Natural killer cells as COVID-19 therapy- Dr. Philippa Kennedy
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13 min
32. Update on the SNG001 drug, an INFβ therapy for COVID-19- Prof. Stephen Holgate
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15 min
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10 min
34. Identification of a new coronavirus-specific RNA export protein complex- Dr. Montse Bárcena-Martin
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17 min
35. The neurological symptoms of COVID-19- Dr. Michael Zandi
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12 min
36. Imperial College London’s saRNA Vaccine - COVAC1- Dr. Katrina Pollock
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15 min
37. Interferon-α2b as a therapy for COVID-19- Prof. Eleanor N. Fish
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11 min
38. Potential long-term health effects of a SARS-CoV-2 infection- Prof. Danny Altmann
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12 min
39. The COVID-19 coronavirus outbreak: October 2020 update- Prof. Jonathan Temte
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9 min
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16 min
41. Rheumatic diseases and COVID-19- Dr. Zachary Wallace
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17 min
42. The cardiovascular complications of SARS-CoV-2 infection- Prof. Srihari Naidu
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20 min
43. Medical wearable devices for tracking symptoms of COVID-19- Prof. John Rogers
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21 min
44. Risk of re-emergence of COVID-19 after exit from lockdown- Dr. Leonardo Lopez
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16 min
45. The evolutionary origin of SARS-CoV-2- Dr. Feng Gao
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15 min
46. Predicting COVID-19 outbreaks by measuring SARS-CoV-2 RNA in sewage sludge- Prof. Jordan Peccia
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12 min
47. Approaches for elucidating genetic susceptibility to SARS-CoV-2- Dr. Kenneth Baillie
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22 min
48. The immune system response to the SARS-CoV-2 virus: July 2020 update- Prof. Paul Klenerman
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22 min
49. The impact of COVID-19 in the elderly and in care homes- Dr. David Strain
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19 min
50. Human challenge trials for vaccines against COVID-19- Prof. Peter Smith
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9 min
51. The development of SARS-CoV-2 vaccines- Prof. Peter Hotez
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15 min
52. Convalescent plasma therapy as a treatment for COVID-19- Dr. Manu Shankar-Hari
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12 min
53. Remdesivir COVID-19 clinical trial- Prof. Mahesh Parmar
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17 min
54. Nanotechnologies in the fight against coronaviruses- Prof. Sabine Szunerits
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15 min
55. The COVID-19 coronavirus outbreak: May 2020 update- Prof. Jonathan Temte
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10 min
56. INFβ therapy for COVID-19: the new SNG001 drug- Prof. Stephen Holgate
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12 min
57. Strategies for exiting the lockdown- Prof. David McCoy
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17 min
58. SARS-CoV-2 human monoclonal antibody therapy- Prof. James Crowe
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8 min
59. An FDA approved salivary test for SARS-CoV-2 infection- Prof. Andrew Brooks
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15 min
60. Development of an intranasal vaccine for SARS-CoV-2- Dr. Scot Roberts
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13 min
61. The immune system response to the SARS-CoV-2 virus: an update- Prof. Paul Klenerman
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8 min
62. A novel AIOD-CRISPR system for diagnosis of SARS-CoV-2- Prof. Changchun Liu
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20 min
63. Development of PRO-140 (Leronlimab) as a treatment for COVID-19- Dr. Jacob Lalezari
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16 min
64. COVID-19 epidemiology and potential treatments: follow up interview- Prof. Ralph Baric
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12 min
65. SARS-CoV-2 vaccine development: where are we now?- Prof. Gary Kobinger
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13 min
66. SARS-CoV-2: What we need to know and possible future therapies- Prof. Stanley Perlman
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8 min
67. SARS-CoV-2 vaccine: current biological targets and considerations- Dr. Adolfo Garcia-Sastre
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20 min
68. The current understanding of the biology of the SARS-CoV-2 virus- Prof. Peter Palese
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16 min
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17 min
70. The immune system response to the SARS-CoV-2 virus- Prof. Paul Klenerman
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9 min
71. SARS-CoV-2 vaccine development- Prof. Stanley Plotkin
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12 min
72. The COVID-19 outbreak: an update on the SARS-CoV-2 virus- Prof. Ralph Baric
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14 min
73. The COVID-19 coronavirus outbreak: a current view- Prof. Jonathan Temte
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17 min
74. The COVID-19 coronavirus outbreak: March 2020 update- Prof. Jonathan Temte
Topics Covered
- Review of the research done since the start of the pandemic
- Current work covering the SARS-CoV-2 variants
- The selection process of monoclonal antibodies for development
- Next steps in the research and future strategies
- The AHEAD100 project i.e. generating neutralizing antibodies for the 100 most likely causes of future epidemics
Biography
Dr. Crowe is Director of the Vanderbilt Vaccine Center and the Ann Scott Carell Professor of Pediatrics, Pathology, Microbiology and Immunology. His laboratory studies the human immune response to infection for a wide variety of major human pathogens, including emerging infections. He is the Director of the Human Immunome Project, an ambitious effort to identify the sequence of all transcripts for human adaptive immune receptors. He is an elected member of the National Academy of Medicine.
Dr. Crowe received his MD degree and pediatrics residency at UNC-Chapel Hill. He received five years of postdoctoral training in the laboratory of Dr. Robert Chanock at the NIH, then completed ID fellowship training in 1996 at Vanderbilt. He has run an independent laboratory at Vanderbilt since then. His research has been supported by a large number of investigator-initiated research awards from NIH, DARPA, DTRA, and foundations. He has trained over 20 investigators who have obtained tenure track positions in academic medical centers.
His work has been published over 350 publications in high-quality journals including Cell, Science, Nature, PNAS USA, the New England Journal of Medicine, and JAMA. He has been the recipient of investigator awards from the March of Dimes, American Society for Microbiology, Pediatric Infectious Diseases Society, and Society for Pediatric Research. He has been awarded the Judson Daland Prize of the American Philosophical Society, the Oswald Avery Award of the IDSA, the Mead Johnson Award for Excellence in Pediatrics, the Outstanding Investigator Award of the American Federation for Medical Research, and the 2010 Siegel Award of the American Pediatric Society. Most recently, he was awarded the 2017 Korsmeyer Award, ASCI and the 2017 the Samuel Rosenthal Foundation Prize in Academic Pediatrics. He is an elected Fellow of AAM, AAAS, ASCI and AAP, IDSA, APS and others. His team was awarded the 2018 Best Academic Research Team, 11th Annual Vaccine Industry Excellence Awards.
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Crowe, J. (2021, June 10). SARS-COV-2 human monoclonal antibody therapy update [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 9, 2025, from https://doi.org/10.69645/IDLA1695.Export Citation (RIS)
Publication History
- Published on June 10, 2021
Financial Disclosures
- Prof. James Crowe has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Audio Interview
SARS-COV-2 human monoclonal antibody therapy update
Published on June 10, 2021
11 min
A selection of talks on Infectious Diseases
Transcript
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