Statistical genetics of infectious diseases

Published on April 30, 2017   62 min

Other Talks in the Series: Statistical Genetics

0:00
Good day, everyone. My name is YY Teo. I'm currently at the National University of Singapore. And I'm the center director for the Center for Infectious Diseases Epidemiology Research. Today, we're going to talk about "Statistical Genetics of Infectious Diseases".
0:18
Now, there has been quite a lot of progress in genomics over the past 15 years. So in 2001, we started with the sequencing of the first draft of the human genome. And we did a spectrum of about 10 years or decade. We have now moved from just sequencing one human, to sequencing thousands of humans and also not just the humans, but also the organisms, the pathogens that are inside and on the surface of the skins of humans. Now given this rapid progress, there has been a lot of opportunities and challenges for the use of genomics to look at a spectrum of diseases.
0:55
So, if we look at the developments that have happened from the period of 2005 to 2015, in these 10 years, we have moved from a case where we knew very little about the genetics or complex traits and common diseases, to knowing in excess of 4,000 specific positions in the human genome that have been found to be associated with the severity of a condition or with the onset of a particular condition.