This is Charles Loprinzi
from Mayo Clinic in Rochester,
I'm happy to talk about
Talking about the incidence,
natural history, measurement,
prevention and treatment aspects.
I'll start off by talking about
the incidence and causative agents.
is a very common problem
who are receiving chemotherapy.
It's probably the most
bothersome chronic toxicity
that we, as oncologists, see
Paclitaxel and oxaliplatin
are two of the biggest offenders,
they cause a fair amount
of neuropathy each time,
and they're used quite frequently.
So I estimate that this is probably
80% of the neuropathy
that we see in clinical oncology.
between the two different drugs.
There are other drugs
that can cause
Other platinum agents
such a cisplatin or carboplatin.
Other taxanes such as docetaxel.
And then there are a variety
of other drugs
and I've listed some there,
that you could see.
These drugs are used less often
than the above noted drugs.