• The Human Genome Project
• 28 min
  1. Major gene families in humans and their evolutionary history

  • Prof. Yoshihito Niimura
• 41 min
  2. Evolution of human mitochondrial DNA variations

  • Prof. Toomas Kivisild
• 51 min
  3. Ethical issues in human population genetics

  • Prof. Henry Greely
• Important Phenotypic Phenomena
• 56 min
  4. Genetics of breast and ovarian cancer

  • Prof. Jeffrey Weitzel
• 53 min
  5. Colorectal cancer and the rare variant hypothesis

  • Prof. Sir Walter Bodmer
• Archived Lectures *These may not cover the latest advances in the field
• 32 min
  6. The genetics of breast and ovarian cancer

  • Dr. Piri Welcsh
• 37 min
  7. Historical and geographical genetic variation: Europe

  • Prof. Antonio Torroni
• 40 min
  8. Linguistic evolution

  • Dr. Merritt Ruhlen
• 37 min
  9. Human microsatellite and minisatellite DNA polymorphisms

  • Dr. James Weber
• 41 min
  10. Human population genetics: lifespan

  • Prof. Kaare Christensen
• 33 min
  11. Major gene families in humans and their evolutionary history

  • Prof. Yoshihito Niimura
  • Prof. Masatoshi Nei
• 34 min
  12. Natural selection and sequence polymorphism

  • Prof. Austin Hughes
• 32 min
  13. Human Y chromosome phylogenetics and phylogeography

  • Prof. Peter Underhill
• 63 min
  14. The peopling of the Americas: new insights from genetic studies

  • Dr. Theodore Schurr
• 48 min
  15. History and geography of human genetic diversity I

  • Prof. Luigi Luca Cavalli-Sforza
• 40 min
  16. History and geography of human genetic diversity II

  • Prof. Luigi Luca Cavalli-Sforza
• 24 min
  17. History and geography of human genetic diversity III

  • Prof. Luigi Luca Cavalli-Sforza
• 46 min
  18. The HapMap project

  • Prof. Andrew Clark
• 37 min
  19. Genetic diseases in the Jewish population

  • Prof. Neil Risch
• 48 min
  20. The genetics of French Canadians

  • Dr. Bernard Brais
  • Dr. Bertrand Desjardins
  • Prof. Damian Labuda
  • Dr. Marc St-Hilaire
  • Prof. Marc Tremblay
  • Prof. Helene Vezina
• 33 min
  21. Human genetic variation of Africa

  • Prof. Joanna Mountain
• 66 min
  22. Evolution: how genes and their variation got here

  • Prof. Kenneth Weiss
• 20 min
  23. Modern human origins

  • Prof. Richard Klein
• 64 min
  24. The human genomes

  • Prof. Gil McVean
• 49 min
  25. The signature of local adaptations in human polymorphism data

  • Dr. Anna Di Rienzo
• 37 min
  26. Genetics of Pakistani populations in an Asian and global context

  • Prof. S. Qasim Mehdi
• 38 min
  27. Cultural evolution

  • Prof. Marcus Feldman
• 45 min
  28. The genetic component to diabetes

  • Dr. Nancy Cox
• 39 min
  29. Human population structure

  • Prof. Noah Rosenberg

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Human lifespan - a heritable trait?
3. Human lifespan - a phenotype of vital importance
4. Lecture outline
5. Changes in human lifespan during the 20th century
6. Female life expectancy in the 20th century
7. Mortality reductions since 1950
8. Record life-expectancy
9. Germany 1980-2000 (1)
10. Germany 1980-2000 (2)
11. Germany 1980-2000 (3)
12. Lifespan - a plastic trait
13. Large variation in lifespan within a birth cohort
14. Chance
15. Lifespan C. elegans
16. Lifespan - summary
17. Lifespan phenotypes
18. Genetic epidemiology of lifespan
19. Family aggregation
20. Family data
21. Twin studies
22. Twin lifespan
23. The individual level of twin studies (1)
24. The individual level of twin studies (2)
25. The individual level of twin studies (3)
26. Human co-twin lifespan
27. Twin design
28. Genetic influence on human lifespan and longevity
29. Danish twin cohorts
30. Swedish twin cohorts
31. Finnish twin cohorts
32. Number of twin pairs
33. Twin-twin plot
34. Relative recurrence risk
35. Lifespan of twin by lifespan of co-twin
36. Change in lifespan of twin by lifespan of co-twin
37. Conclusion
38. The genetic architecture of human longevity
39. Genetic study design in longevity research
40. What has been found so far?
41. The frequencies of ApoE alleles vary with age
42. Molecular pathways that lengthen lifespan
43. Other good candidates
44. Guidelines for future studies
45. Collaborators

Topics Covered

• Human lifespan as a heritable trait
• Lifespan phenotypes
• Genetic epidemiology of human lifespan
• The genetic architecture of human longevity
• Genetic study designs in longevity research

Links

Series:

• Human Population Genetics I

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on August 13, 2020

Financial Disclosures

• Prof. Kaare Christensen has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.