• The Human Genome Project
• 28 min
  1. Major gene families in humans and their evolutionary history

  • Prof. Yoshihito Niimura
• 41 min
  2. Evolution of human mitochondrial DNA variations

  • Prof. Toomas Kivisild
• 51 min
  3. Ethical issues in human population genetics

  • Prof. Henry Greely
• Important Phenotypic Phenomena
• 56 min
  4. Genetics of breast and ovarian cancer

  • Prof. Jeffrey Weitzel
• 53 min
  5. Colorectal cancer and the rare variant hypothesis

  • Prof. Sir Walter Bodmer
• Archived Lectures *These may not cover the latest advances in the field
• 32 min
  6. The genetics of breast and ovarian cancer

  • Dr. Piri Welcsh
• 37 min
  7. Historical and geographical genetic variation: Europe

  • Prof. Antonio Torroni
• 40 min
  8. Linguistic evolution

  • Dr. Merritt Ruhlen
• 37 min
  9. Human microsatellite and minisatellite DNA polymorphisms

  • Dr. James Weber
• 41 min
  10. Human population genetics: lifespan

  • Prof. Kaare Christensen
• 33 min
  11. Major gene families in humans and their evolutionary history

  • Prof. Yoshihito Niimura
  • Prof. Masatoshi Nei
• 34 min
  12. Natural selection and sequence polymorphism

  • Prof. Austin Hughes
• 32 min
  13. Human Y chromosome phylogenetics and phylogeography

  • Prof. Peter Underhill
• 63 min
  14. The peopling of the Americas: new insights from genetic studies

  • Dr. Theodore Schurr
• 48 min
  15. History and geography of human genetic diversity I

  • Prof. Luigi Luca Cavalli-Sforza
• 40 min
  16. History and geography of human genetic diversity II

  • Prof. Luigi Luca Cavalli-Sforza
• 24 min
  17. History and geography of human genetic diversity III

  • Prof. Luigi Luca Cavalli-Sforza
• 46 min
  18. The HapMap project

  • Prof. Andrew Clark
• 37 min
  19. Genetic diseases in the Jewish population

  • Prof. Neil Risch
• 48 min
  20. The genetics of French Canadians

  • Dr. Bernard Brais
  • Dr. Bertrand Desjardins
  • Prof. Damian Labuda
  • Dr. Marc St-Hilaire
  • Prof. Marc Tremblay
  • Prof. Helene Vezina
• 33 min
  21. Human genetic variation of Africa

  • Prof. Joanna Mountain
• 66 min
  22. Evolution: how genes and their variation got here

  • Prof. Kenneth Weiss
• 20 min
  23. Modern human origins

  • Prof. Richard Klein
• 64 min
  24. The human genomes

  • Prof. Gil McVean
• 49 min
  25. The signature of local adaptations in human polymorphism data

  • Dr. Anna Di Rienzo
• 37 min
  26. Genetics of Pakistani populations in an Asian and global context

  • Prof. S. Qasim Mehdi
• 38 min
  27. Cultural evolution

  • Prof. Marcus Feldman
• 45 min
  28. The genetic component to diabetes

  • Dr. Nancy Cox
• 39 min
  29. Human population structure

  • Prof. Noah Rosenberg

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Contents
3. Multigene family (1)
4. Multigene family (2)
5. Color vision genes
6. Red/ green-pigment gene duplication
7. Color vision genes in New World Monkeys
8. Full trichromatic vision in primates
9. Evolutionary models for multigene families
10. Olfactory receptors (1)
11. Olfactory receptors (2)
12. OR gene expression
13. Features of ORs
14. The olfactory system uses combinatorial coding
15. OR genes in humans
16. OR genes in the human genome
17. Distribution of OR genes in human chromosomes
18. Evolutionarily closely related genes
19. Organization of OR genomic clusters
20. Summary of the observations
21. Comparison of OR genes: humans vs. mice (1)
22. Comparison of OR genes: humans vs. mice (2)
23. Comparison of OR genomic clusters
24. Chromosomes translocation occurred in mouse
25. The mouse cluster is usually larger
26. Less functional OR human genes (1)
27. Less functional OR human genes (2)
28. Gene duplications after human-mouse divergence
29. Phylogenetic tree of the entire set of OR genes
30. No. of inactivated functional genes in the MRCA
31. Estimated number of functional genes
32. Evolution of OR genes in vertebrates (1)
33. Evolution of OR genes in vertebrates (2)
34. Number of OR genes in six species
35. Phylogenetic tree from 5 species
36. Condensed tree (70% level) for 310 OR genes
37. Number of functional OR genes in different groups
38. Evolutionary dynamics of vertebrate OR genes
39. Summary
40. Other chemosensory receptor genes
41. Receptors for chemosensation
42. Vomeronasal receptors
43. Taste receptors
44. No. of chemosensory receptor genes in vertebrates
45. Conclusions
46. Thank you

Topics Covered

• Multigene family
• Olfactory Receptors (ORs)
• OR genes in humans
• Comparison of OR genes between humans and mice
• Evolution of OR genes in vertebrates
• Other chemosensory receptor genes

Links

Series:

• Human Population Genetics I

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on February 25, 2021

Financial Disclosures

• Prof. Yoshihito Niimura has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
• Prof. Masatoshi Nei has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.