Negative pressure wound therapy: mechanisms of action and clinical uses

Published on October 7, 2014   32 min
0:00
Hello, I'm Doctor Dennis Orgill, and today I'd like to talk about negative pressure wound therapy, mechanism of action, and clinical uses.
0:11
For financial disclosures, I've had passed research funding and have been a consultant and an expert witness for KCI.
0:20
Today we'll begin by discussing the history and technology transfer of negative pressure wound therapy devices, we'll review the biology of skin stretching, and we'll talk about the four primary mechanisms of negative pressure wound therapy, which include macrodeformation, microdeformation, fluid removal, and a moist wound environment. We'll then discuss secondary mechanisms which include, angiogenesis, inflammation, regulation of matrix metalloproteinases, and their effect on peripheral nerves. Finally, we'll go over some case examples including sternal wounds, open abdomens, groin wounds, and skin grafts following a brief discussion.
Hide

Negative pressure wound therapy: mechanisms of action and clinical uses

Embed in course/own notes