Hello, my name is Mihaly Hajos.
I am from Yale School of Medicine.
In my talk, I would like to
give you an insight to drug
discovery for neurological
and psychiatric disorders.
I will also focus on some
challenges in neuropharmacology
and how these obstacles could be
addressed by collaborative efforts
between academic and
Use of mind-altering
or psychoactive drugs,
mostly plants or plant products,
dates to prehistoric times.
demonstrated their use
dating back at least 10,000 years.
Some of these plants, for
their active ingredients,
are still used or abused today.
And some even have found their
way to clinical practice.
However, until very
recently, mode of actions
of these the mind-altering
plants or substances
have been totally unknown since
it was only in the 20th century
that we gained some insight to
basic mechanisms of brain function.
modification of mood or sensation
by these plants clearly indicated
that even the highest level
of brain function can be
altered, also providing hope
for potential treatment
of mental disorders.
Eventually, a new
was born, neuropharmacology,
studying drug effects
or neural function from molecular
to behavioral responses.