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- Introduction
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16 min
1. Psychopharmacology: structural aspects of the brain- Prof. Brian Leonard
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66 min
2. The nature of chemical neurotransmission- Prof. Brian Leonard
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28 min
3. Psychotropic drugs- Prof. Brian Leonard
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26 min
4. Psychopharmacology of anxiety disorders- Prof. Brian Leonard
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35 min
5. Psychopharmacology of depression- Prof. Brian Leonard
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48 min
6. Psychopharmacology of mania and schizophrenia- Prof. Brian Leonard
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45 min
7. The role of stress and immune system in psychiatric disorders- Prof. Brian Leonard
- Introduction to Genetic Investigations of Complex Traits
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39 min
- Genetics and Pharmacokinetics of Psychotropic Drugs
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34 min
9. Genetics of phase I enzymes- Prof. Aiming Yu
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36 min
10. Phase II metabolism- Prof. Ann Daly
- Genetics and Pharmacodynamics of Psychotropic Drugs
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25 min
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25 min
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51 min
13. Pharmacogenetics of antidepressants- Prof. Alessandro Serretti
- Clinical Applications of Psychopharmacogenetics
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41 min
14. Of genes and drugs: genetic determinants of adverse drug reactions- Dr. Mario Masellis
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35 min
15. Cocaine and amphetamine addiction genetics- Dr. Gerome Breen
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29 min
- Archived Lectures *These may not cover the latest advances in the field
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47 min
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37 min
18. Genetic determinants of metabolism: clinical applications in psychiatry- Prof. Julia Stingl (formerly Kirchheiner)
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36 min
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47 min
20. Genetic polymorphisms influencing response to lithium- Prof. Alessandro Serretti
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28 min
21. Genetic determinants of antipsychotic-induced weight gain- Prof. Gavin Reynolds
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59 min
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50 min
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37 min
24. Genetic determinants of agranulocytosis- Dr. Michael Dettling
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52 min
25. Genetic polymorphisms influencing the response of antidepressants- Prof. Alessandro Serretti
Printable Handouts
Navigable Slide Index
- Introduction
- Lecture plan
- Antipsychotic drug treatment
- Major side effects of the treatment of schizophrenia
- Antipsychotic drug treatment: newer drugs
- Antipsychotic drug-induced weight gain
- Diabetes following antipsychotic treatment
- Antipsychotic drug effects on weight gain
- Weight gain studies in drug naive populations
- Antipsychotic drug-induced weight gain: questions
- Pharmacogenetic studies in schizophrenia
- Receptor mechanisms of antipsychotic weight gain
- 5-HT2C receptors and weight gain
- 5-HT2C receptors, genes and weight gain
- Pharmacogenetics of antipsychotic weight gain
- Association study of 5HT2C receptor gene: Chinese
- Expression of the Chinese study in a different way
- Association study of 5HT2C receptor gene: Spanish
- Mechanisms of the promoter polymorphism (1)
- Mechanisms of the promoter polymorphism (2)
- Olanzapine-induced weight gain
- Functional mechanisms
- Consequences of antipsychotic treatment
- Leptin
- Leptin, fat and food intake
- Leptin promoter polymorphism and weight gain
- Leptin association study
- Blood leptin and 5-HT2C genotype
- Genetic testing for drug-induced weight gain?
- Metabolic consequences - future challenges
Topics Covered
- Antipsychotic drugs: limitations and side effects
- Drug-induced weight gain
- Severity and consequences
- Receptor mechanisms
- Role of 5-HT2C receptor
- Pharmacogenetics of antipsychotic weight gain: 5-HT2C promoter polymorphism
- Functional mechanism of polymorphism
- Role of leptin and leptin-promoter polymorphism
- Role of genetic testing
- Future directions
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Reynolds, G. (2007, October 1). Genetic determinants of antipsychotic-induced weight gain [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/JVNV2270.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Gavin Reynolds has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
