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Navigable Slide Index

1. Introduction
2. Pharmacogenetic phenotypes
3. Enzymes assays for pharmacokinetics
4. Polymorphism to DME activity: CYP2D6
5. Polymorphism to DME activity: CYP2C9
6. CYP2C9 genotypes in warfarin patients
7. Pharmacogenetics: the key markers to test for
8. Typical process for genotyping samples
9. Rapid sample analysis
10. Methods for sequence analysis
11. Homogeneous PCR assays
12. Complex probe technologies
13. HyBeacon probes
14. HyBeacon assays: SNP discrimination
15. Differential probe hybridisation
16. Development of CYP2D6*4 assay
17. Analysis of CYP2D6*4 SNP
18. Development of a factor V Leiden assay
19. Analysis of factor V Leiden
20. Sickle cell anaemia
21. HyBeacon multiplex potential
22. The secret is in the dribble
23. Direct sample analysis
24. Point-of-care diagnostics
25. Automated sample analysis
26. Traditional vs point-of-care diagnostics
27. Pharmacogenetics: avoiding adverse drug reactions
28. Link DME activity to prescription: CYP2D6
29. Personalising medication
30. Applications - consent and ethics
31. The future

Topics Covered

• Key pharmacogenetic targets
• Minimizing laboratory processing
• Homogenous reactions and DNA probes
• Rapid and simple allele discrimination
• Point of care

Links

Series:

• Psychopharmacogenetics

Categories:

• Genetics & Epigenetics
• Methods
• Pharmaceutical Sciences

Talk Citation

Debenham, P. (2007, October 1). Rapid methods for the genetic determination of pharmacokinetic status [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 3, 2024, from https://doi.org/10.69645/NTDH2741.
Export Citation (RIS)

Publication History

• Published on October 1, 2007
• Archived on February 25, 2021

Financial Disclosures

• Dr. Paul Debenham has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.