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Navigable Slide Index

1. Introduction
2. Contents of lecture
3. The hypothalmic-pitultary-adrenal axis (HPA axis)
4. Cortisol and brain repair
5. Role of stress in psychiatric disorders
6. Dexamethasone suppression test
7. Relationship between 3 systems
8. Effect of stress on HPA axis and immune system
9. HPA axis in chronic depression
10. Definition of psychoimmunology
11. Historical aspects of psychoimmunology
12. Relevant brain cells
13. Immune system in psychiatric disorders
14. Immune system effect on the brain
15. Can brain affect the immune system
16. Mechanism of brain effect on immune system
17. What are cytokines
18. Cytokines effect in psychiatric disorders
19. Inflammatory processes in psychiatric disorders
20. Antidepressants' effects on inflammatory processes
21. Immune changes in schizophrenia
22. Microglia are over-active in schizophrenia

Topics Covered

• The relationship between neurotransmitters and the HPA axis
• The role of stress in psychiatric disorders
• Effects of stress or depression on the HPA axis and the immune system
• The role of the immune system in psychiatric disorders
• Basic aspects of psychoimmunology

Links

Series:

• Psychopharmacogenetics

Categories:

• Immunology
• Neuroscience

Therapeutic Areas:

• Immunology & Inflammation
• Neurology

Talk Citation

Leonard, B. (2007, October 1). The role of stress and immune system in psychiatric disorders [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 15, 2025, from https://doi.org/10.69645/OHMP4328.
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Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Brian Leonard has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.