Registration for a live webinar on 'Innovative Vaccines and Viral Pathogenesis: Insights from Recent Monkeypox Research' is now open.
See webinar detailsWe noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Types of diabetes
- Epidemiology of type 2 diabetes
- Diabetes risk factors
- Pathophysiology
- Progression of type 2 diabetes
- Insulin resistance, secretion, and diabetes risk
- Insulin response during GTT
- Mechanisms of type 2 diabetes
- Obesity trends among U.S. adults
- Diagnosed diabetes and obesity (2007)
- Race & ethnicity in diabetes
- Prevalence of obesity & diabetes worldwide
- Measures of adiposity
- Adiposity and ethnicity
- BMI and ethnicity
- BMI equivalents in men
- BMI equivalents in women
- Measures of central obesity
- Measurements using CT
- Visceral adipose tissue and ethnicity
- BMI, waist circumference and visceral fat
- Japanese Americans and diabetes
- Study measurements
- Follow-up exams
- Fat and risk of diabetes
- Annual DM incidence
- Characteristics of subjects by diabetes status
- Subcutaneous vs. visceral obesity
- Visceral adiposity and ethnic differences
- Can body fat distribution be changed?
- The diabetes prevention program
- Results for men
- Results for women
- Lifestyle intervention
- Mean weight change
- DPP results
- Concerns
- DPPOS
- Subjects' weight change
- Subjects' diabetes incidence
- Conclusions of the study
- Further questions
- Genes or environment?
- Cardiovascular health study
- Other attributes
- Genotype study
- Methods for genotype study
- SNPs used in the study
- Genotype scores
- Cumulative incidence of diabetes
- Contribution of genetic risk score
- Conclusions
- Thank you
Topics Covered
- Epidemiology of Type 2 Diabetes
- Diabetes Risk Factors
- Pathophysiology of Type 2 Diabetes
- Progression of Type 2 Diabetes
- Insulin Resistance, Secretion, and Diabetes Risk
- Insulin Response during Glucose Tolerance Testing
- Mechanisms of Type 2 Diabetes
- Obesity Trends
- Obesity and Diabetes Prevalence in Select Nations
- Measures of Adiposity and Ethnicity
- BMI Equivalents by Ethnicity
- Measures of Central Adiposity
- Japanese American Community Diabetes Study
- Risk of Diabetes by Subcutaneous and Visceral Fat Areas
- Ectopic Fat Deposition Hypothesis
- Body Composition Does Not Explain Ethnic Risk Disparity
- Changing Body Fat Distribution
- Diabetes Prevention Program (DPP)
- DPP Results
- Type 2 Diabetes Risk
- Genes or Environment?
- Single Nucleotide Polymorphisms of Interest
- Genotype Score Distribution by Diabetes Outcome
- Diabetes Risk by Genotype Score
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Boyko, E. (2013, June 11). Type 2 diabetes [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 2, 2024, from https://doi.org/10.69645/TDEJ6952.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Edward Boyko has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Cardiovascular & Metabolic
Transcript
Please wait while the transcript is being prepared...
0:00
My name is Dr. Ed Boyko,
and I'll be talking today
on the subject of Type 2 diabetes.
I'm a professor at the
University of Washington School
of Medicine in Seattle,
Washington USA.
0:14
I'll cover a number
of aspects of Type
2 diabetes, as shown
in this outline slide.
I'll mainly focus
on the epidemiology
and pathophysiology
of Type 2 diabetes.
I'll talk about ethnic
differences in diabetes risk,
and also with regard to body
composition, a risk factor
for diabetes, and I'll
talk about efforts
at prevention of Type 2 diabetes.
And I will not be talking about
the prevention of Type 1 diabetes.
I also will not be covering
the treatment of Types 1
or 2 diabetes, or
diabetic complications.
0:53
There are multiple diabetes types.
Type 1 diabetes is
mainly characterized
by a deficiency in the
production of insulin.
Type 2 diabetes is characterized
by impaired action of insulin
and relatively deficient
insulin secretion.
Type 1.5 diabetes
shares characteristics
of both Type 1 and Type 2 diabetes.
There are immune markers present
and also characteristic impaired
action of insulin.
Secondary diabetes is
due to other causes,
such as chronic pancreatitis
from alcohol or other reasons,
which results in impaired
insulin secretion,
or because of the administration
of a medication such as prednisone
or another corticosteroid, which
results in impaired action
of insulin because of increased
resistance to its action,
MODY, or Maturity
Onset Diabetes of Youth
is a hereditary form of
diabetes due to a mutation
in autosomal dominant genes.
The mutation results in defects
in insulin secretion or release.
It's referred to as monogenic
diabetes to distinguish it
from Types 1 and 2 diabetes,
which are polygenic,
and also of environmental origin.
Type 2 diabetes has
become much more frequent
in prevalence over
the past 30 years.
The epidemiology of Type 2 diabetes
is shown on the next slide.