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1. Introduction
2. Full depth articular cartilage structure
3. Structural heterogeneity of cartilage
4. Cartilage has a poor repair potential
5. Lesion grades
6. ACI: Autologous Chondrocyte Implantation
7. Chondrocyte expansion
8. Reseach on articular cartilage
9. Cell division in cartilage
10. Bovine MCP joint
11. Progenitor isolation
12. Differential adhesion assay
13. Colony forming efficiency after adhesion to FN
14. Integrin expression
15. Expansion in culture from single colonies
16. Expansion in culture: maintenance of phenotype
17. Transfected developing chick wing bud
18. Chondroprogenitor plasticity
19. Summary
20. Do stem/progenitors exist in mature tissue...
21. Unilateral/unicompartmental O.A.of tibial plateau
22. Human cartilage adheres to FN
23. Human cartilage is clonogemic
24. Mechanisms that regulate stem cells
25. Notch/ligand expression
26. Role of Notch1 in regulation stem cells population
27. Notch cleavage and ligand binding
28. Non-specific Notch inhibition abolishes clonality
29. S2 inhibition by TIMP 3 inhibits CFE
30. Mechanism of Notch1 activation
31. Notch siRNA
32. Non-specific activation by Jagged 1
33. Human cartilage notch 1 expression
34. Summary
35. References
36. References
37. Acknowledgements

Topics Covered

• Cartilage repair
• Cartilage progenitor isolation and characterization
• Human articular cartilage progenitors
• The role of Delta/Notch signalling in progenitor proliferation

Links

Series:

• Stem Cells and Regenerative Medicine

Categories:

• Cell Biology

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Charles Archer has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.