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- Epidemiology and risk factors
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1. Epidemiology of COPD
- Dr. David Mannino
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2. COPD in never smokers
- Dr. Sundeep Salvi
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3. Genetics of chronic obstructive pulmonary disease (COPD)
- Prof. Martin Tobin
- Phenotypes of COPD
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4. COPD and asthma: similarities and differences
- Prof. Peter Barnes
- Pathophysiology and mechanisms of COPD
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5. The pathology of chronic obstructive pulmonary disease
- Prof. James Hogg
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6. The continuum of COPD: a physiological perspective
- Prof. Denis O'Donnell
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7. Inflammatory and immune mechanisms in COPD
- Prof. Peter Barnes
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8. Mechanisms of COPD exacerbations and relation to exacerbation therapy
- Prof. Wisia Wedzicha
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9. Protease-antiprotease balance
- Prof. Robert Stockley
- Therapy and management
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10. Updates in chronic obstructive pulmonary disease (COPD)
- Dr. Omar S. Usmani
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11. Long-acting bronchodilators in COPD
- Prof. Bart Celli
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12. Treatment of COPD exacerbations
- Prof. Antonio Anzueto
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13. Pulmonary rehabilitation: history, promise and problems
- Prof. Richard Casaburi
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14. Lung volume reduction: advances in COPD
- Dr. Nick Hopkinson
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15. New pharmacological therapies for COPD
- Prof. Peter Barnes
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16. The Salford lung study in COPD
- Dr. Dave Leather
- COPD case studies
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17. COPD treatment case I: COPD with “bronchitis attacks”
- Dr. Janwillem Kocks
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18. COPD treatment case II: COPD with asthma as child
- Dr. Janwillem Kocks
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19. COPD treatment case III: COPD with pre-diabetes
- Dr. Janwillem Kocks
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20. Tailoring care for advanced COPD
- Prof. Wissam Chatila
- Archived Lectures *These may not cover the latest advances in the field
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21. Alpha-1 antitrypsin deficiency: state of the art
- Dr. Jamie Stoller
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22. Oxidative stress in COPD
- Prof. William MacNee
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23. Managing co-morbidity in COPD
- Dr. John Hurst
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24. Clinical phenotypes of COPD
- Prof. Jørgen Vestbo
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25. Pulmonary rehabilitation: focusing on rehabilitative exercise
- Prof. Richard Casaburi
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26. Genetics of COPD
- Prof. Ian Hall
Printable Handouts
Navigable Slide Index
- Introduction
- Hyperinflation
- Lung volume reduction for COPD
- Lung volume reduction surgery (LVRS)
- LVRS vs. medical therapy
- Changes in lung volumes post LVRS
- Surgical mortality in practice is higher
- The national emphysema treatment trial (NETT)
- NETT - inclusion and exclusion
- NETT - results
- Kaplan-Meier estimates of death probability
- NETT - initial results
- LVRS after the NETT
- Longer term outcomes of NETT
- Patient selection for LVRS
- Surgery for bullae
- Operating volumes during exercise in bullectomy
- Elective surgery for giant bullous emphysema
- ATS / ERS COPD guidelines
- Other methods of lung volume reduction
- Bronchoscopic lung volume reduction
- Valves
- Successful lung volume reduction using valve (1)
- Successful lung volume reduction using valve (2)
- Change in endurance time after BLVR
- Successful BLVR is associated with survival
- The VENT trial (1)
- The VENT trial (2)
- Baseline characteristics - The VENT trial
- Primary outcomes at 6 months - The VENT trial
- Adverse events at 90 days - VENT study
- Heterogeneity effects on response to treatment
- VENT trial - summary
- Spiration valves
- Airway bypass (1)
- Airway bypass- demonstration
- CASSA report
- Airway bypass (2)
- EASE trial
- EASE trail - methods and participants
- EASE trail - peri-procedure safety
- 6 month primary safety endpoint
- Bronchoscopy review of exhale stents
- Short-lived benefits for airway bypass
- Airway bypass - improvement needed
- Future approaches
- Transpleural airway bypass 'spiracles'
- Extrapulmonary airway bypass
- Device - continual development
- Lung volume reduction coil PneumRx inc (1)
- Lung volume reduction coil PneumRx inc (2)
- Biological lung volume reduction
- Blood lung volume reduction
- Bronchoscopic Thermal Vapor Ablation
- Conclusion
Topics Covered
- Hyperinflation in COPD
- Lung volume reduction surgery (LVRS)
- Bullectomy
- Bronchoscopic techniques including valves, airway bypass, coils, steam and fibrin glue
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Hopkinson, N. (2012, July 31). Lung volume reduction: advances in COPD [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/KOZH1722.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Nick Hopkinson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.