• Clinical Introduction
• 49 min
  1. Frontotemporal dementia

  • Prof. Bruce Miller
• 57 min
  2. Parkinson disease

  • Prof. Stanley Fahn
• 35 min
  3. Atypical parkinsonian syndromes

  • Dr. David Burn
• 40 min
  4. Huntington's disease

  • Prof. Roger Barker
• Neuroimaging
• 22 min
  5. Molecular brain imaging (PET) in diseases with dementia

  • Prof. Karl Herholz
• Pathology, Genetic and Molecular Aspects (1)
• 42 min
  6. A molecular understanding of Alzheimer's disease

  • Prof. John Hardy
• 33 min
  7. Neuropathology of neurodegenerative disorders

  • Prof. Jillian Kril
• 52 min
  8. The role of MAPT (Tau) in neurodegenerative disease: one bullet with many triggers

  • Dr. Michael Hutton
• 12 min
  9. Ubiquitination and Alzheimer related disorders

  • Prof. John Mayer
• Pathology, Genetic and Molecular Aspects (2)
• 46 min
  10. The molecular biology of Huntington's disease

  • Prof. David C. Rubinsztein
• 46 min
  11. Metals, oxidative stress and neurodegeneration

  • Prof. Ashley Bush
• Latest Developments in the Field
• 46 min
  12. Animal models of tauopathy

  • Prof. David Westaway
• 61 min
  13. Parkinson's disease and transplants

  • Prof. Roger Barker
• Archived Lectures *These may not cover the latest advances in the field
• 29 min
  14. Neuropathology of neurodegenerative disorders

  • Prof. Jillian Kril
• 36 min
  15. Motor neurone disease: molecular basis

  • Prof. Kevin Talbot
• 51 min
  16. Alzheimer's disease (AD)

  • Prof. John Hodges
• 53 min
  17. Frontotemporal dementia syndromes

  • Prof. John Hodges
• 38 min
  18. Motor neurone disease: clinical aspects

  • Prof. Kevin Talbot
• 26 min
  19. Neuro-imaging in dementia: using MRI in routine work-up

  • Prof. Philip Scheltens
• 53 min
  20. Prion diseases

  • Prof. Pierluigi Gambetti
• 38 min
  21. Mitochondrial disorders and neurodegeneration

  • Prof. Anthony Schapira
• 21 min
  22. Neurodegenerative disease: expression levels of normal sequence pathogenic proteins contribute to risk of disease

  • Prof. John Hardy
• 44 min
  23. Mutations in parkinsonian syndromes

  • Dr. Andrew Singleton
• 42 min
  24. Experimental therapies in Alzheimer's disease: the development and use of mouse models

  • Prof. David Westaway
• 32 min
  25. Frontotemporal dementia

  • Prof. Bruce Miller

Printable Handouts

PDF

Navigable Slide Index

1. Intro slide
2. Scope of the presentation
3. Progressive supranuclear pulsy
4. Charles Dickens and PSP?
5. Descriptive epidemiology of PSP
6. The "typical" PSP case
7. Clinical features
8. Falls in PSP vs. Parkinson's disease
9. Cognitive and behavioural changes
10. NINDS-SPSP criteria (1996)
11. Atypical clinical features in PSP
12. Natural history of PSP
13. Pathology of PSP
14. PSP: clinical and genetic correlation
15. Recent drug studies in PSP I
16. Recent drug studies in PSP II
17. Multiple system atrophy
18. Descriptive epidemiology of MSA
19. MSA: clinicopathological features
20. Motor features of MSA
21. Autonomic failure in MSA
22. MSA and cognitive impairment
23. Quinn diagnostic criteria (1994)
24. When to suspect MSA
25. Physical signs in MSA
26. Natural history of MSA
27. Management of parkinsonism in MSA
28. Management of autonomic failure in MSA I
29. Management of autonomic failure in MSA II
30. Corticobasal degeneration
31. General features of CBD
32. CBD: diagnostic features
33. Investigations of atypical parkinsonian disorders
34. Structural MRI in PSP and MSA
35. VBM in PSP: grey matter loss
36. MR spectroscopy in PSP
37. Functional imaging (PET & SPECT)
38. 18F-dopa PET in parkinsonism
39. Sphincter EMG and parkinsonism
40. Future therapeutic directions
41. Conclusion

Topics Covered

• Types of atypical parkinsonian syndromes
• Descriptive epidemiology
• Clinical features
• Cognitive and neurobehavioural aspects
• Pathology and aetiology
• Natural history
• Structural and functional investigations
• Clinical management
• Future research directions

Links

Series:

• Neurodegenerative Diseases

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Dr. David Burn has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.